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Native Mouse Apotransferrin

Cat.No. : Trf-70M
  • Specification
  • Gene Information
  • Related Products
Description : Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and in prevention of iron loss via the kidney. Stored in bone marrow as TF-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypo-proteinemias and nephritic syndrome; increases are found in pregnancy, iron-deficiency anemias and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important factor used in defined culture media.
Source : Mouse Plasma
Species : Mouse
Form : Lyophilized
Molecular Mass : 80.0 kDa
Purity : Purity by SDS-PAGE: ≥98%
Usage : For Research Use Only! Not For Use in Humans.
Notes : Centrifuge the vial prior to opening
Storage : -20°C
Storage Buffer : Lyophilized from 20 mM Na phosphate, pH 7.4 and 150 mM NaCI.
Shipping : Gel pack
Gene Name : Trf transferrin [ Mus musculus ]
Official Symbol : Trf
Synonyms : HP; Tf; Tfn; hpx; Cd176; AI266983; serotransferrin; siderophilinbeta-1 metal-binding globulin; hypotransferrinemia with hemochromatosis
Gene ID : 22041
mRNA Refseq : NM_133977
Protein Refseq : NP_598738
UniProt ID : Q921I1
Chromosome Location : 9 F1-F3; 9 55.03 cM
Pathway : HIF-1 signaling pathway, organism-specific biosystem; Iron Homeostasis, organism-specific biosystem; Mineral absorption, organism-specific biosystem
Function : ferric iron binding; ferric iron transmembrane transporter activity; metal ion binding; metal ion binding; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can TF proteins be used for diagnosing diseases? 03/19/2021

Yes, abnormalities in TF proteins can serve as diagnostic markers for certain diseases.

Are there any approved drugs that target TF proteins? 11/27/2020

Yes, some drugs target TF proteins, especially in the treatment of cancer.

How do TF proteins contribute to autoimmune diseases? 08/25/2020

TF proteins can trigger or suppress immune responses, making them relevant in understanding autoimmune diseases.

How do TF proteins play a crucial role in clinical applications? 03/16/2016

TF proteins are vital for understanding disease mechanisms and can be targeted for therapeutic purposes.

Are there any clinical tests or assays that measure TF protein levels? 03/05/2016

Yes, various assays, like ELISA and Western blot, can be used to quantify TF protein levels.

Customer Reviews (3)

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Reviews
08/01/2020

    Their team of experts is not only knowledgeable about the TF protein but is also dedicated to assisting researchers like myself in overcoming any challenges that may arise.

    01/22/2018

      This high-quality protein is crucial for the success of my experiments, ensuring that I obtain reliable and meaningful scientific findings.

      04/11/2016

        The TF protein is of exceptional quality, making it a perfect fit for my experimental needs.

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