Native Human Hemopexin

• Cat.No.: HPX-207H

Specification

• Description: Hemopexin is a single-chain protein belonging to the family of blood transport proteins. It binds to heme released into the bloodstream during the degradation process. Recent studies have demonstrated that hemopexin acts as an extracellular antioxidant against hemoglobin-mediated damage in inflammation. Hemopexin protects against heme toxicity and conserves and recycles iron. Abnormal levels of hemopexin are associated with hemolytic anemia, chronic neuromuscular disease, and acute intermittent porphyria.
• Source: Human Plasma
• Species: Human
• Form: Lyophilized
• Molecular Mass: MW: 57,000
• Endotoxin: <1.0 eu/mg by fluorogenic assay, lonza,>
• Purity: >= 95% by SDS-PAGE
• Usage: For research use only.
• Quality Control Test: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
• Stability: >1 year
• Storage: -20°C
• Storage Buffer: 11.9 mM phosphate, 137 mM CaCl, 2.7 mM KCI, pH 7.4

Gene Information

• Gene Name: HPX hemopexin [ Homo sapiens ]
• Official Symbol: HPX
• Synonyms: HPX; hemopexin; beta-1B-glycoprotein; HX; FLJ56652
• Gene ID: 3263
• mRNA Refseq: NM_000613
• Protein Refseq: NP_000604
• MIM: 142290
• UniProt ID: P02790
• Chromosome Location: 11p15.5-p15.4
• Function: binding; heme transporter activity; metal ion binding; protein binding