Native Human Leucine-rich Alpha 2 Glycoprotein-1 (LRG1)

• Cat.No.: LRG1-240H

Specification

• Description: LRG1 binds cytochrome c, an initiator/amplifier of programmed cell death (apoptosis), and by binding cytochrome c, is thought to play a role in cell survival. LRG1 is a biomarker associated with several cancers, including non-small cell lung cancer, colorectal cancer, and pancreatic cancer. Recent studies have shown it is three-fold more abundant in ovarian cancer serum compared to non-cancer control serum. LRG1 levels are only moderately correlated with CA125 levels.
• Source: Human Plasma
• Species: Human
• Form: Lyophilized
• Molecular Mass: 50,000 by SDS-PAGE
• Purity: >= 95% by SDS-PAGE.
• Applications: Positive reaction to anti-LRG1 on Western Blot
• Usage: For research use only.
• Quality Control Test: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
• Stability: >1 year
• Storage: <=>
• Storage Buffer: 20 mM Tris, 20 mM NaCl, pH 7.5

Gene Information

• Gene Name: LRG1 leucine-rich alpha-2-glycoprotein 1 [ Homo sapiens ]
• Official Symbol: LRG1
• Synonyms: LRG1; leucine-rich alpha-2-glycoprotein 1; leucine-rich alpha-2-glycoprotein; leucine rich alpha 2 glycoprotein; LRG; 1300008B03Rik; 2310031E04Rik; HMFT1766; FLJ45787
• Gene ID: 116844
• mRNA Refseq: NM_052972
• Protein Refseq: NP_443204
• MIM: 611289
• UniProt ID: P02750
• Chromosome Location: 19
• Function: molecular_function