Native Human Platelet Factor 4

• Cat.No.: PF4-253H

Specification

• Description: A heparin-neutralizing protein which is contained in platelet storage granules. Platelet Factor 4 is released during aggregation, but its actual role in normal or abnormal hemostatis is unknown.
• Source: Human Platelet
• Species: Human
• Form: Lyophilized
• Molecular Mass: MW: 27,100
• Usage: For research or further manufacturing use only.
• Quality Control Test: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
• Stability: >1 year
• Storage: <=>
• Storage Buffer: 20 mM Tris, pH 8.3, with 1.5 M NaCl

Gene Information

• Gene Name: PF4 platelet factor 4 [ Homo sapiens ]
• Official Symbol: PF4
• Synonyms: PF4; platelet factor 4; chemokine (C X C motif) ligand 4; CXCL4; SCYB4; iroplact; oncostatin-A; C-X-C motif chemokine 4; chemokine (C-X-C motif) ligand 4; PF-4; MGC138298
• Gene ID: 5196
• mRNA Refseq: NM_002619
• Protein Refseq: NP_002610
• MIM: 173460
• UniProt ID: P02776
• Chromosome Location: 4q12-q21
• Pathway: CXCR3-mediated signaling events, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Common Pathway, organism-specific biosystem
• Function: chemokine activity; heparin binding