Native Bovine S-100b Protein

• Cat.No.: S100B-257B

Specification

• Description: S-100 is a low molecular weight, cytoplasmic, calcium binding protein. It is traditionally found in the brain, heart and muscle tissue. S-100 has two subunits (alpha-chain and beta-chain) and exists in several different forms. The alpha-alpha homodimer is referred to in literature as either the S-100αα or S-100a(0), the beta-beta homodimer is referred to in literature as S-100b and the alpha-beta heterodimer is referred to in literature as S-100a. ART purifies a mixture of all forms (S-100), S-100αα (<5% beta chain contamination by western blot), and s-100b><10% alpha chain contamination by western>
• Source: Bovine Brain
• Species: Bovine
• Form: Lyophilized
• Molecular Mass: 6000
• Purity: >=95% by SDS-PAGE
• Usage: For research or further manufacturing use only.
• Quality Control Test: Prepared from tissue collected int the contiguous United States from animals under 30 months of age at a USDA inspected facility.Animals were inspected ante and post mortem and found free of infections diseases.
• Stability: >1 year
• Storage: -20°C
• Storage Buffer: 50 mM Tris-HCl, pH 7.5, 50 mM NaCl, 100 M DTT

Gene Information

• Gene Name: S100B S100 calcium binding protein B [ Bos taurus ]
• Official Symbol: S100B
• Synonyms: protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B; S100 protein, beta polypeptide
• Gene ID: 525716
• mRNA Refseq: NM_001034555
• Protein Refseq: NP_001029727
• UniProt ID: P02638
• Chromosome Location: chromosome: 1
• Pathway: Activated TLR4 signalling, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; DEx/H-box helicases activate type I IFN and inflammatory cytokines production, organism-specific biosystem
• Function: RAGE receptor binding; S100 protein binding; calcium ion binding