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Recombinant Chicken AMY2A

Cat.No. : AMY2A-1116C
Product Overview : Recombinant Chicken AMY2A full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Chicken
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : AMY2A amylase, alpha 2A; pancreatic [ Gallus gallus (chicken) ]
Official Symbol : AMY2A
Gene ID : 414140
Protein Refseq : NP_001001473
UniProt ID : F1NF53

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (13)

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How is the AMY2A protein regulated in the body? 06/23/2022

The regulation of the AMY2A protein is primarily mediated by hormonal signals and the presence of carbohydrates in the digestive system. When carbohydrates are consumed, the pancreas releases the hormone called pancreatic amylase. This hormone stimulates the production and release of alpha-amylase, including the AMY2A protein, from the pancreas into the small intestine to aid in carbohydrate digestion.

Are there any populations or ethnic groups that have a higher or lower AMY2A gene copy number compared to others? 03/01/2022

Research suggests that there is some variation in AMY2A gene copy number among different populations and ethnic groups.

Can variations in the AMY2A gene impact carbohydrate metabolism? 06/19/2021

Yes, variations in the AMY2A gene, such as copy number variations, have been associated with differences in carbohydrate metabolism. Individuals with a higher number of AMY2A gene copies tend to have higher levels of alpha-amylase enzyme production, which may result in more efficient carbohydrate digestion and absorption.

Are there any health conditions associated with mutations in the AMY2A gene? 09/28/2020

While mutations specifically in the AMY2A gene are not commonly associated with specific health conditions, variations in the copy number of the AMY2A gene have been linked to certain metabolic and digestive disorders. For example, individuals with a lower number of AMY2A gene copies may have reduced amylase production, leading to impaired carbohydrate digestion and potential susceptibility to conditions like insulin resistance and obesity.

Is the AMY2A protein involved in any processes outside of carbohydrate digestion? 03/09/2020

The primary role of the AMY2A protein is in carbohydrate digestion. However, there is emerging evidence suggesting potential roles for alpha-amylase in processes beyond digestion. For example, some studies have suggested that amylase may play a role in adipogenesis (the formation of fat cells) and lipid metabolism. However, further research is needed to fully understand these potential roles and their implications.

Are there any dietary factors that can affect the expression or activity of the AMY2A protein? 06/07/2019

It is believed that dietary factors can influence the expression and activity of the AMY2A protein. For example, diets high in carbohydrates may stimulate the production and release of alpha-amylase, including the AMY2A protein, to aid in carbohydrate digestion.

Can the AMY2A gene copy number be tested through genetic testing? 11/20/2018

Yes, it is possible to determine the AMY2A gene copy number through genetic testing. Various methods, such as quantitative polymerase chain reaction (qPCR) or droplet digital PCR (ddPCR), can be used to assess the copy number of the AMY2A gene.

Can the AMY2A protein be used as a diagnostic or therapeutic target for any conditions? 05/31/2018

The AMY2A protein is currently not used as a diagnostic or therapeutic target for specific conditions. However, understanding variations in the AMY2A gene and their impact on carbohydrate metabolism may have implications for personalized nutrition and diet recommendations. Additionally, further research may uncover potential therapeutic interventions targeting the AMY2A protein or related pathways for certain metabolic disorders.

How does the AMY2A gene copy number affect carbohydrate digestion? 03/26/2018

The AMY2A gene encodes the alpha-amylase enzyme, which is responsible for breaking down complex carbohydrates (starches) into smaller sugar molecules. The number of AMY2A gene copies a person has can influence the overall production of alpha-amylase protein and, consequently, their ability to digest carbohydrates. Individuals with a higher AMY2A gene copy number typically have higher alpha-amylase production, leading to more efficient carbohydrate digestion.

Is the AMY2A protein linked to any diseases? 09/04/2017

The AMY2A protein itself is not directly linked to diseases. However, dysregulation of carbohydrate metabolism due to variations in AMY2A gene copy number or other genetic factors can contribute to the development of certain conditions. For instance, alterations in carbohydrate metabolism can impact blood sugar control and insulin sensitivity, which are key factors in the development of type 2 diabetes.

Are there any genetic variations or mutations associated with the AMY2A gene? 05/15/2017

Yes, there are genetic variations and mutations associated with the AMY2A gene. One well-known variation is the copy number variation (CNV) of the AMY2A gene, which refers to the number of gene copies an individual has. Humans can have different numbers of AMY2A gene copies, with some individuals having more copies than others. This variation may affect the amount of alpha-amylase enzyme produced and potentially influence carbohydrate digestion and metabolism.

How does the AMY2A protein function in carbohydrate digestion? 01/18/2017

The AMY2A protein functions by cleaving the glycosidic bonds between sugar units in complex carbohydrates. It hydrolyzes starch, which is a polysaccharide made up of glucose units, into smaller sugar molecules like maltose. These smaller sugars are more easily absorbed in the small intestine and can be further metabolized by the body for energy.

Can variations in AMY2A gene copy number be inherited? 10/23/2016

Yes, variations in AMY2A gene copy number can be inherited. The number of copies of the AMY2A gene a person has is determined by their genetic makeup, which is a combination of genetic material inherited from both parents. Therefore, if a parent has a certain number of AMY2A gene copies, their child has a chance of inheriting a similar number of gene copies.

Customer Reviews (4)

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Reviews
08/18/2022

    Manufacturers should ensure the consistency and quality of AMY2A protein products.

    09/01/2020

      They can offer detailed characterization data, including purity, stability, and functional assessments, to support researchers' confidence in using the protein in their trials.

      06/10/2020

        Manufacturers can support researchers in developing assays to measure AMY2A protein levels or activity specific to their clinical trial settings.

        06/19/2019

          This may involve guidance in selecting appropriate detection methods, providing assay components, or optimizing protocols for optimal performance and sensitivity.

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