Recombinant Human ADAM 10, His-tagged
Cat.No. : | ADAM10-265H |
Product Overview : | RecombinantHuman ADAM 10 comprises a 459 amino acid fragment (214-672) corresponding to the ADAM 10 extracellular domain minus the signal peptide and pro-sequence and is expressed in E. coli with an amino-terminal hexahistidine tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ADAM10-265H |
Description : | ADAM 10 is a member of the ADAM family of membrane-anchored cell surface proteins, which contain both a disintegrin and a metalloprotease domain. ADAM 10 is expressed in a wide variety of tissues and resides on both the cell surface and within the cytoplasm. ADAM10 has been implicated in proteolytic release of a number of cell surface proteins in particular TNF alpha. |
Source : | E.coli. |
Purity : | >95% by SDS-PAGE |
Form : | Liquid |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
Gene Name : | ADAM10 ADAM metallopeptidase domain 10 [ Homo sapiens ] |
Synonyms : | ADAM10; CD156c; HsT18717; MADM; kuz; AD10; KUZ; EC 3.4.24.81; A desintegrin and metalloprotease domain 10; Mammalian disintegrin-metalloprotease; Kuzbanian protein homolog; CDw156c antigen; AD10; CDw156; kuzbanian; CD156c antigen; a disintegrin and metalloprotease domain 10; ADAM metallopeptidase domain 10; ADAM10 ADAM metallopeptidase domain 10. |
Gene ID : | 102 |
mRNA Refseq : | NM_001110 |
Protein Refseq : | NP_001101 |
MIM : | 602192 |
UniProt ID : | O14672 |
Chromosome Location : | 15q2; 15q22 |
Pathway : | Epithelial cell signaling in Helicobacter pylori infection; Signaling by EGFR; Signaling by Notch |
Function : | SH3 domain binding; integrin binding; metal ion binding; metalloendopeptidase activity; peptidase activity; protein homodimerization activity; protein kinase binding; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
ADAM10-73H | Recombinant Human ADAM10 Protein, His-tagged | +Inquiry |
ADAM10-306M | Recombinant Mouse ADAM10 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAM10-5834C | Recombinant Chicken ADAM10 | +Inquiry |
ADAM10-0691H | Recombinant Human ADAM10 Protein (Thr214-Ser504), N-His tagged | +Inquiry |
Adam10-961M | Active Recombinant Mouse Adam10 Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (4)
Ask a questionADAM10 protein can cleave TNF-α and E-cadherin, etc.
The addition of the GST tag helps protect the recombinant protein from extracellular protease degradation and improves its stability.
The protein size of ADAM10 precursor is larger than that of ADAM10 active.
ADAD1 is currently also used in the research of Alzheimer's disease and diabetic retinopathy, etc.
Customer Reviews (3)
Write a reviewDuring the experiment, the technician helped me solve the problems in a timely and accurate manner.
The ADAM10 proteins purchased from your company is suitable for WB.
Received high quality protein products and obtained satisfactory experimental results.
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