Recombinant Human AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)

• Cat.No.: AHSA1-322H
• Product Overview: Recombinant human AHSA1 protein was expressed in E. coli and purified by using conventional chromatography techniques (320 aa, 36.1 kDa).

Specification

• Cat. No.: AHSA1-322H
• Description: The co-chaperone Aha1 (Activator of HSP90 ATPase-1) binds the middle domain of Hsp90(amino acid 272-627) and is proposed to function as an ATPase-activating protein that competes with p23 and other co-chaperones for Hsp90 binding.
• Source: E.coli.
• Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM EDTA.
• Molecular Weight: 36.1 kDa (320 aa).
• Purity: > 95% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method).
• Sequence: MATNVNNWHW TERDASNWST DKLKTLFLAV QVQNEEGKCE VTEVSKLDGE ASINNRKGKL IFFYEWSVKL NWTGTSKSGV QYKGHVEIPN LSDENSVDEV EISVSLAKDE PDTNLVALMK EEGVKLLREA MGIYISTLKT EFTQGMILPT MNGESVDPVG QPALKTEERK AKPAPSKTQA RPVGVKIPTC KITLKETFLT SPEELYRVFT TQELVQAFTH APATLEADRG GKFHMVDGNV SGEFTDLVPE KHIVMKWRFK SWPEGHFATI TLTFIDKNGE TELCMEGRGI PAPEEERTRQ GWQRYYFEGI KQTFGYGARL
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: AHSA1
• Synonyms: AHSA1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); p38; AHA1; C14orf3; chromosome 14 open reading frame 3; activator of heat shock 90kDa protein ATPase homolog 1.
• Gene ID: 10598
• mRNA Refseq: NM_012111.2
• Protein Refseq: NP_036243.1
• MIM: 608466
• UniProt ID: O95433
• Chromosome Location: 14q24
• Function: ATPase activator activity; chaperone binding.