Recombinant Human Biliverdin Reductase B

• Cat.No.: BLVRB-135H
• Product Overview: Recombinant BLVRB protein was expressed in E.coli and purified by using conventional chromatography techniques,22.1 kDa (206 aa).

Specification

• Cat. No.: BLVRB-135H
• Description: Biliverdin reductase B (BLVRB) is an enzyme (EC 1.3.1.24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis.
• Sequences of amino acids: MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ
• Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 8.5) containing 1 mM DTT, 10% glycerol
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: BLVRB biliverdin reductase B (flavin reductase (NADPH)) [ Homo sapiens ]
• Synonyms: BVR-B; BVRB; EC 1.5.1.30,EC 1.3.1.24 ; FLR; FR; GHBP; MGC117413; SDR43U1; Biliverdin reductase B; Biliverdin-IX beta-reductase; Green heme-binding protein; NADPH-dependent diaphorase; NADPH-flavin reductase; biliverdin reductase B (flavin reductase (NADPH)); flavin reductase (NADPH); short chain dehydrogenase/reductase family 43U, member 1; BLVRB
• Gene ID: 645
• mRNA Refseq: NM_000713
• Protein Refseq: NP_000704
• MIM: 600941
• UniProt ID: 30043
• Chromosome Location: 19q13.1-q13.2
• Pathway: Porphyrin and chlorophyll metabolism
• Function: biliverdin reductase activity; binding; coenzyme binding; flavin reductase activity; oxidoreductase activity