Recombinant Human MALT1, MYC/DDK-tagged

• Cat.No.: MALT1-28H
• Product Overview: Recombinant Human MALT1, transcript variant 1, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Description: This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Source: HEK293 cells
• Species: Human
• Tag: MYC/DDK
• Molecular Mass: 92.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: MALT1 MALT1 paracaspase [ Homo sapiens (human) ]
• Official Symbol: MALT1
• Synonyms: MALT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; MLT; mucosa-associated lymphoid tissue lymphoma translocation protein 1; paracaspase; caspase-like protein; MALT associated translocation; MALT lymphoma-associated translocation; MALT-lymphoma associated translocation; MLT1; DKFZp434L132
• Gene ID: 10892
• mRNA Refseq: NM_006785
• Protein Refseq: NP_006776
• MIM: 604860
• UniProt ID: Q9UDY8
• Chromosome Location: 18q21
• Pathway: Activation of NF-kappaB in B cells; B cell receptor signaling pathway; BCR signaling pathway
• Function: cysteine-type endopeptidase activity; peptidase activity; protein binding