Native Human MUC16 protein
Cat.No. : | MUC16-1H |
Product Overview : | Native Human MUC16 was purified in Human Ascites Fluid. |
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Description : | MUC16 played an important role in many functions. |
Source : | Human Ascites Fluid |
Species : | Human |
Form : | Liquid in phosphate buffered saline, pH 7.4 with sucrose |
Purity : | > 95% (SDS-PAGE) |
Storage : | Store at -20 centigrade |
Concentration : | 100 - 700 kU/mL (Roche Elecsys EIA) |
Preservative : | 0.05% Sodium Azide |
Publication : |
A Mucin 16 bispecific T cell–engaging antibody for the treatment of ovarian cancer (2023)
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Gene Name : | MUC16 mucin 16, cell surface associated [ Homo sapiens ] |
Official Symbol : | MUC16 |
Synonyms : | MUC16; mucin 16, cell surface associated; mucin-16; CA125; FLJ14303; CA-125; MUC-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125; |
Gene ID : | 94025 |
mRNA Refseq : | NM_024690 |
Protein Refseq : | NP_078966 |
MIM : | 606154 |
UniProt ID : | Q8WXI7 |
Chromosome Location : | 19p13.2 |
Pathway : | Metabolism of proteins, organism-specific biosystem; O-linked glycosylation of mucins, organism-specific biosystem; Post-translational protein modification, organism-specific biosystem; Termination of O-glycan biosynthesis, organism-specific biosystem; |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
MUC16-01H | Recombinant Human MUC16 Protein, His tagged | +Inquiry |
MUC16-0066H | Recombinant Human MUC16 Protein | +Inquiry |
MUC16-42H | Active Recombinant Human MUC16 Protein, His-tagged | +Inquiry |
MUC16-28H | Recombinant Human MUC16 Protein, C-Fc-Avi tagged, Biotinylated | +Inquiry |
MUC16-43H | Active Recombinant Human MUC16 Protein, Fc-Avi-tagged, Biotinylated | +Inquiry |
◆ Native Protein | ||
CDA002 | Active Native Human MUC16 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMUC16 works with other mucins and immune components to maintain epithelial barrier function and immune responses.
It aids in forming the mucosal barrier, protecting against pathogens and mechanical damage.
Targeting MUC16 in cancer therapy, especially in ovarian cancer, could be effective in inhibiting tumor growth and spread.
Altered MUC16 activity can impact the body's defense against inflammation and infection.
MUC16, a mucin protein, is essential for maintaining the protective mucous layer on epithelial surfaces.
MUC16 is associated with cancer progression, particularly in ovarian cancer, where it may facilitate tumor growth and metastasis.
Genetic variations in MUC16 can lead to differences in mucosal integrity and potentially influence cancer susceptibility.
Customer Reviews (3)
Write a reviewCritical for decision-making. Supports our research endeavors.
Expert service quality. Valuable for research integrity.
Dependable partner in experiments. Consistent and trustworthy.
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