Active Native Human Glutamate Pyruvate Transaminase (GPT)

• Cat.No.: GPT-65H

Specification

• Source: Human Heart
• Species: Human
• Form: Purified, Liquid
• Bio-activity: 620 Units/mL @ 37°C measured
• Purity: Contaminants: GOT 1.3% ALP<0.1%>GGT<0.1%>
• Unit Definition: One unit will catalyze the transamination of one micromole of L-alanine to alpha-ketoglutarate, forming L-glutamate and pyruvate per minute at 37oC and pH 7.4. Measured at 340 nm as one equimolar amount of NAD produced by a coupled reaction.
• Characteristic: Protein: 18 mg/mL (Coomassie) Specific Activity: 34 Units/mg Protein
• Applications: Specific methodologies have not been tested using this product.
• Usage: FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY
• Notes: Centrifuge before opening to ensure complete recovery of vial contents.
• Storage: Store at 2-8°C. DO NOT FREEZE!
• Concentration: Activity: 620 Units/mL @ 37°C
• Storage Buffer: Ammonia Sulfate Suspension

Gene Information

• Gene Name: GPT glutamic-pyruvate transaminase (alanine aminotransferase) [ Homo sapiens ]
• Official Symbol: GPT
• Synonyms: GPT; glutamic-pyruvate transaminase (alanine aminotransferase); alanine aminotransferase 1; ALT1; GPT1; GPT 1; glutamic-alanine transaminase 1; glutamic--alanine transaminase 1; glutamic--pyruvic transaminase 1; glutamate pyruvate transaminase 1; AAT1
• Gene ID: 2875
• mRNA Refseq: NM_005309
• Protein Refseq: NP_005300
• UniProt ID: P24298
• Chromosome Location: 8q24.2-qter
• Pathway: Alanine and aspartate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem
• Function: 1-aminocyclopropane-1-carboxylate synthase activity; L-alanine:2-oxoglutarate aminotransferase activity; L-alanine:2-oxoglutarate aminotransferase activity; pyridoxal phosphate binding; transaminase activity