Recombinant Human Dystrobrevin Binding Protein 1
Cat.No. : | DTNBP1-308H |
Product Overview : | Recombinant human Dysbindin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography technique (307 aa, 34.6 kDa). |
- Specification
- Gene Information
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Cat. No. : | DTNBP1-308H |
Description : | Dysbindin is a ubiquitously expressed protein that binds to alpha- and beta-dystrobrevins, components of the dystrophin-associated protein complex (DPC) in both muscle and nonmuscle cells. Dysbindin has been strongly implicated in schizophrenia (SZ) susceptibility by a series of independent genetic association and gene expression studies. Among its known functions, dysbindin is part of a protein complex, termed the biogenesis of lysosome-related organelles complex 1 (BLOC-1), the molecular components of which might be involved in the regulation of vesicular trafficking and dendrite branching. Dysbindin effects for brain volume and cortical thickness appear driven by different neurobiological processes. |
Source : | E.coli. |
Formulation : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 100 mM NaCl, 0.5 mM DTT, 20% glycerol. |
Molecular Weight : | 34.6 kDa (307aa). |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 0.5 mg/ml (determined by Bradford assay). |
Sequence : | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMLS AHWEKKKTSL VELQEQLQQL PALIADLESM TANLTHLEAS FEEVENNLLH LEDLCGQCEL ERCKHMQSQQ LENYKKNKRK ELETFKAELD AEHAQKVLEM EHTQQMKLKE RQKFFEEAFQ QDMEQYLSTG YLQIAERREP IGSMSSMEVN VDMLEQMDLM DISDQEALDV FLNSGGEENT VLSPALGPES STCQNEITLQ VPNPSELRAK PPSSSSTCTD SATRDISEGG ESPVVQSDEE EVQVDTALAT SHTDREATPD GGEDSDS |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | DTNBP1 |
Synonyms : | DTNBP1; dystrobrevin binding protein 1; SDY; DBND; HPS7; My031; FLJ30031; MGC20210; DKFZp564K192; C20orf35; CK1BP; HSMNP1; OTTHUMP00000031115; OTTHUMP00000031116; OTTHUMP00000031117; OTTHUMP00000031118; OTTHUMP00000031119; OTTHUMP00000031120; OTTHUMP00000016062; SCF apoptosis response protein 1; casein kinase-1 binding protein; chromosome 20 open reading frame 35; dysbindin (dystrobrevin binding protein 1) domain containing 2; dysbindin. |
Gene ID : | 84062 |
mRNA Refseq : | NM_032122.3 |
Protein Refseq : | NP_115498.2 |
MIM : | 607145 |
UniProt ID : | Q96EV8 |
Chromosome Location : | 6p22.3 |
Function : | identical protein binding. |
Products Types
◆ Recombinant Protein | ||
DTNBP1-2546M | Recombinant Mouse DTNBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DTNBP1-1625R | Recombinant Rat DTNBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Dtnbp1-683R | Recombinant Rat Dtnbp1 Protein, His-tagged | +Inquiry |
DTNBP1-2902H | Recombinant Human DTNBP1 Protein, GST-tagged | +Inquiry |
Dtnbp1-682M | Recombinant Mouse Dtnbp1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
DTNBP1-6796HCL | Recombinant Human DTNBP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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