Recombinant Zebrafish TBK1
Cat.No. : | TBK1-3904Z |
Product Overview : | Recombinant Zebrafish TBK1 full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Zebrafish |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC. |
Storage Buffer : | PBS buffer |
Gene Name : | tbk1 TANK-binding kinase 1 [ Danio rerio (zebrafish) ] |
Official Symbol : | TBK1 |
Gene ID : | 692289 |
mRNA Refseq : | NM_001044748 |
Protein Refseq : | NP_001038213 |
UniProt ID : | Q0GKD6 |
Products Types
◆ Recombinant Protein | ||
TBK1-2161H | Recombinant Human TBK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TBK1-01H | Active Recombinant Human TBK1 Protein | +Inquiry |
TBK1-4458R | Recombinant Rhesus Macaque TBK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TBK1-010H | Active Recombinant Human TBK1 Protein | +Inquiry |
Tbk1-6315M | Recombinant Mouse Tbk1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
TBK1-1745HCL | Recombinant Human TBK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionTBK1 is a critical component of the cGAS-STING pathway, which senses cytosolic DNA and triggers type I interferon responses. TBK1 phosphorylates STING, initiating downstream signaling events.
TBK1 is involved in selective autophagy processes by phosphorylating autophagy receptors and initiating the clearance of damaged organelles or pathogens. This contributes to maintaining cellular homeostasis and responding to stress conditions.
TBK1 plays a dual role in inflammation, acting as both a pro-inflammatory and anti-inflammatory mediator. Dysregulation of TBK1 is implicated in autoimmune disorders and inflammatory diseases, highlighting its complex regulatory role.
TBK1 dysfunction has been associated with neurodegenerative diseases, particularly amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The precise mechanisms linking TBK1 to these diseases are areas of active research.
TBK1 plays a crucial role in the activation of the transcription factor IRF3, leading to the induction of type I interferons. This activation is triggered by the recognition of viral nucleic acids or other pathogen-associated molecular patterns.
Customer Reviews (3)
Write a reviewImpressed with the quality and swift delivery.
Five stars for this amazing lab product!
Top-quality product, superb customer service!
Ask a Question for All TBK1 Products
Required fields are marked with *
My Review for All TBK1 Products
Required fields are marked with *
Inquiry Basket