Recombinant Human Proteasome (prosome, macropain) 26S Subunit, Non-ATPase, 10
Cat.No. : | PSMD10-358H |
Product Overview : | Recombinant human PSMD10 was expressed in E.coli and purified by conventional chromatography techniques, 24.4kDa (226aa). |
- Specification
- Gene Information
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Cat. No. : | PSMD10-358H |
Description : | PSMD10 is an oncoprotein commonly overexpressed in most hepatocellular carcinomas. Gankyrin interacts with S6 ATPase of the 19S regulatory particle of the 26S proteasome. It is known to play a role in the regulation of the phosphorylation of the retinoblastoma protein by CDK4, and to enhance the ubiquitinylation of p53 by MDM2. Gankyrin consists of 7 ankyrin repeats and is structurally similar to I kappa Bs. |
Source : | Escherichia Coli. |
Form : | Liquid. In Phosphate buffered saline (pH7.4), 10% glycerol |
Purity : | > 95% by SDS - PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MEGCVSNLMV CNLAYSGKLE ELKESILADK SLATRTDQDS RTALHWACSA GHTEIVEFLL QLGVPVNDKD DAGWSPLHIA ASAGRDEIVK ALLGKGAQVN AVNQNGCTPL HYAASKNRHE IAVMLLEGGA NPDAKDHYEA TAMHRAAAKG NLKMIHILLY YKASTNIQDT EGNTPLHLAC DEERVEEAKL LVSQGASIYI ENKEEKTPLQ VAKGGLGLIL KRMVEG |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 [ Homo sapiens ] |
Synonyms : | Gankyrin; OTTHUMP00000023827; OTTHUMP00000023828; dJ889N15.2; gankyrin; p28; 26S proteasome regulatory subunit p28; ankyrin repeat protein; hepatocellular carcinoma-associated protein p28-II; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10; proteasome 26S non-ATPase subunit 10; PSMD10; 26S proteasome non-ATPase regulatory subunit 10. |
Gene ID : | 5716 |
mRNA Refseq : | NM_002814 |
Protein Refseq : | NP_002805 |
MIM : | 603480 |
UniProt ID : | O75832 |
Chromosome Location : | Xq22.3 |
Function : | protein binding |
Products Types
◆ Recombinant Protein | ||
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PSMD10-3486R | Recombinant Rhesus Macaque PSMD10 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSMD10-6927H | Recombinant Human Proteasome (prosome, macropain) 26S Subunit, Non-ATPase, 10 | +Inquiry |
PSMD10-4785R | Recombinant Rat PSMD10 Protein | +Inquiry |
◆ Lysates | ||
PSMD10-2755HCL | Recombinant Human PSMD10 293 Cell Lysate | +Inquiry |
PSMD10-2756HCL | Recombinant Human PSMD10 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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