Recombinant Human L-Selectin,His-tagged

• Cat.No.: SELL-279H
• Product Overview: Recombinant Human L-selectin comprises a 294 amino acid fragment (39-332) corresponding to the mature L-Selectin extracellular domain and is expressed in E. coli with an amino-terminal hexahistidine tag.

Specification

• Cat. No.: SELL -279H
• Description: L-Selectin belongs to a family of divalent cationdependent carbohydrate-binding glycoproteins or adhesion molecules. L-Selectin is expressed constitutively on lymphocytes, monocytes and granulocytes and interacts specifically with carbohydrate groups on activated endothelial cells. L-Selectin may be shed by proteolytic cleavage and circulating levels in biological fluids may be used as an indicator of various pathological conditions.
• Source: E.coli.
• Purity: >95% by SDS-PAGE
• Form: Liquid
• Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Gene Information

• Gene Name: SELL selectin L [ Homo sapiens ]
• Synonyms: Leukocyte Selectin; L-SEL; Leukocyte adhesion molecule; LAM-1; Leukocyte cell adhesion molecule LECAM-1; TQ1; CD62L; Leukocyte surface antigen Leu-8; DREG; lymph node homing receptor LNHR; MEL-14; SELL; selectin L; LAM1; LSEL; LYAM1; Leu-8; PLNHR; hLHRc; LECAM1; Lyam-1; Leu-8 antigen; lymph node homing receptor; leukocyte adhesion molecule-1; lymphocyte adhesion molecule 1; LNHR; gp90-MEL; CD62 antigen-like family member L; CD62L antigen; Leukocyte-endothelial cell adhesion molecule 1.
• Gene ID: 6402
• mRNA Refseq: NM_000655
• Protein Refseq: NP_000646
• MIM: 153240
• UniProt ID: P14151
• Chromosome Location: 1q23-q25
• Pathway: Cell adhesion molecules (CAMs); Hemostasis; Signaling in Immune system
• Function: glycosphingolipid binding; heparin binding; protein binding; sugar binding