Recombinant Human selectin P, His-tagged

• Cat.No.: SELP-282H
• Product Overview: Recombinant Human P-selectin comprises a 566 amino acid fragment (197-761) corresponding to the cysteine rich complement control protein domain and is expressed in E. coli with an amino-terminal hexahistidine tag.

Specification

• Cat. No.: SELP -282H
• Description: P-Selectin belongs to a family of divalent cationdependent carbohydrate-binding glycoproteins or adhesion molecules. P-Selectin is expressed transiently on the surface of activated platelets and endothelial cells. Secreted P-selectin is thought to play a key role in the adhesion of platelets to monocytes and neutrophils during an inflammatory response. Levels of P-Selectin may be elevated in a number of pathological conditions.
• Source: E.coli.
• Purity: >95% by SDS-PAGE
• Form: Liquid
• Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Gene Information

• Gene Name: SELP selectin P (granule membrane protein 140kDa, antigen CD62) [ Homo sapiens ]
• Synonyms: P-SEL; Platelet Alpha-Granule Membrane Protein; CD62; CD62P; Granulocyte Membrane Protein GRMP; GMP140; LECAM-3; SELP; FLJ45155; GRMP; PADGEM; PSEL; selectin P (granule membrane protein 140kDa, antigen CD62); LECAM3; selectin P; OTTHUMP00000032609; granulocyte membrane protein; platelet alpha-granule membrane protein; leukocyte-endothelial cell adhesion molecule 3; CD62 antigen-like family member P; CD62P antigen; Granule membrane protein 140; selectin P (granule membrane protein 140kD, antigen CD62).
• Gene ID: 6403
• mRNA Refseq: NM_003005
• Protein Refseq: NP_002996
• MIM: 173610
• UniProt ID: P16109
• Chromosome Location: 1q22-q25
• Pathway: Cell adhesion molecules (CAMs); Hemostasis; Signaling in Immune system
• Function: fucose binding; glycosphingolipid binding; heparin binding; lipopolysaccharide binding; oligosaccharide binding; protein binding; sialic acid binding; sugar binding