Recombinant Zebrafish ADRA2A
Cat.No. : | ADRA2A-11832Z |
Product Overview : | Recombinant Zebrafish ADRA2A full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Zebrafish |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC. |
Storage Buffer : | PBS buffer |
Gene Name : | adra2a adrenoceptor alpha 2A [ Danio rerio (zebrafish) ] |
Official Symbol : | ADRA2A |
Gene ID : | 266750 |
mRNA Refseq : | NM_207637 |
Protein Refseq : | NP_997520 |
UniProt ID : | Q1MTI7 |
Products Types
◆ Recombinant Protein | ||
ADRA2A-197R | Recombinant Rat ADRA2A Protein, His (Fc)-Avi-tagged | +Inquiry |
ADRA2A-379H | Recombinant Human ADRA2A Protein | +Inquiry |
Adra2a-3330R | Recombinant Rat Adra2a, His-tagged | +Inquiry |
ADRA2A-3331P | Recombinant Pig ADRA2A, His-tagged | +Inquiry |
ADRA2A-541R | Recombinant Rat ADRA2A Protein | +Inquiry |
◆ Lysates | ||
ADRA2A-9000HCL | Recombinant Human ADRA2A 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2180 | cAMP ADRA2A CHO-K1 GPCR Assay Kit | +Inquiry |
Kit-2179 | ADRA2A CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (19)
Ask a questionThe potential side effects of targeting ADRA2A depend on the specific compound used and the dose administered. Alpha-2 adrenergic agonists can cause sedation, dry mouth, constipation, and other side effects, while alpha-2 adrenergic antagonists can cause increased heart rate, blood pressure, and other cardiovascular effects.
Some genetic variations in the ADRA2A gene have been associated with increased risk of certain diseases, including anxiety disorders, ADHD, and hypertension.
Some research suggests that lifestyle factors such as exercise, diet, and stress reduction may influence ADRA2A expression and activity, although more research is needed in this area.
Yes, the alpha-2 adrenergic receptor family includes three subtypes - ADRA2A, ADRA2B, and ADRA2C - all of which share some common functions, but also have some distinct roles in different tissues and physiological processes.
Yes, genetic variations in the ADRA2A gene have been identified that affect receptor expression or activity, and have been associated with various diseases such as ADHD and depression.
Yes, targeting the ADRA2A receptor has been investigated as a potential treatment for hypertension, with studies showing that alpha-2 adrenergic agonists can lower blood pressure by reducing sympathetic nervous system activity.
The ADRA2A receptor is present in several organs including the brain, kidneys, lungs, blood vessels, and smooth muscle cells. Its function is to regulate the release of neurotransmitters, hormones, and enzymes, and to modulate blood pressure, heart rate, and gastrointestinal motility.
Studies have suggested that targeting the ADRA2A receptor could be beneficial for improving cognitive functions such as working memory and attention in certain populations, such as individuals with ADHD.
Yes, some research suggests that targeting the ADRA2A receptor could be a potential therapeutic strategy for treating addiction, particularly nicotine addiction, as it may modulate dopamine release and reward circuits in the brain.
There is some evidence to suggest that ADRA2A expression levels may be useful as a biomarker for certain diseases, such as ADHD and PTSD, although more studies are needed in this area.
ADRA2A stands for alpha-2A adrenergic receptor, a protein that is part of the adrenergic receptor family.
Targeting the ADRA2A receptor is being investigated for its therapeutic applications in several diseases, such as hypertension, anxiety, depression, and attention deficit hyperactivity disorder (ADHD).
ADRA2A agonists bind to and activate the receptor, resulting in reduced sympathetic nervous system activity and decreased release of norepinephrine. ADRA2A antagonists, on the other hand, block the receptor, leading to increased sympathetic nervous system activity and elevated levels of norepinephrine.
The ADRA2A receptor is part of the alpha-2 adrenergic receptor family, whereas the ADRA1A receptor is part of the alpha-1 adrenergic receptor family. In terms of function, the ADRA2A receptor is primarily responsible for inhibiting the release of noradrenaline, whereas the ADRA1A receptor enhances its release.
ADRA2A is thought to modulate cognitive function by regulating the release of neurotransmitters such as norepinephrine and dopamine, which are involved in attention, working memory, and other cognitive processes.
Alpha-2 adrenergic agonists such as clonidine and dexmedetomidine bind to the ADRA2A receptor and activate it, leading to inhibition of noradrenaline release and decreasing blood pressure, heart rate, and stress response.
Yes, genetic variations in the ADRA2A gene may influence an individual's response to medications that target the receptor, such as clonidine and dexmedetomidine.
Yes, targeting the ADRA2A receptor can have adverse effects, such as sedation, depression, and hypotension, particularly when using high doses or in individuals with certain medical conditions.
ADRA2A-targeted treatments have potential applications in various diseases and conditions, including hypertension, addiction, ADHD, PTSD, and depression. However, more research is needed to fully understand the therapeutic potential and limitations of targeting the receptor in each of these contexts.
Customer Reviews (5)
Write a reviewAfter carefully considering various sources of protein, I have confidently chosen the protein from this particular supplier.
I was impressed with the superb technical support provided by the manufacturer, which has been instrumental in addressing any questions or concerns I have had with ease.
Based on my evaluation, the ADRA2A protein is of exceptional quality and purity, and will undoubtedly meet my experimental needs.
I am highly satisfied with the quality of the product as well as the exceptional customer service and technical support I have received.
With their experienced team readily available, I feel confident in my ability to achieve accurate and reliable results.
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