Recombinant Human Synaptosomal-associated Protein, 23kDa
Cat.No. : | SNAP23-303H |
Product Overview : | Recombinant SNAP23 protein was expressed in E.coli and purified by using conventional chromatography techniques (211 aa, 23.3 kDa). |
- Specification
- Gene Information
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Cat. No. : | SNAP23-303H |
Description : | SNAP23, a non-neuronal SNAP25 homologue, is a target SNARE ubiquitously expressed on the plasma membrane and other intracellular membranes. SNAP23 is widely believed to involve in exocytotic membrane fusion in most cells that do not express SNAP-25. |
Source : | E.coli. |
Formulation : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0). |
Molecular Weight : | 23.3 kDa (211 aa). |
Purity : | > 90% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Sequence : | MDNLSSEEIQ QRAHQITDES LESTRRILGL AIESQDAGIK TITMLDEQKE QLNRIEEGLD QINKDMRETE KTLTELNKCC GLCVCPCNRT KNFESGKAYK TTWGDGGENS PCNVVSKQPG PVTNGQLQQP TTGAASGGYI KRITNDARED EMEENLTQVG SILGNLKDMA LNIGNEIDAQ NPQIKRITDK ADTNRDRIDI ANARAKKLID S |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | SNAP23 |
Synonyms : | SNAP23; synaptosomal-associated protein, 23kDa; SNAP23A; SNAP23B; HsT17016; SNAP-23; OTTHUMP00000161263; Vesicle-membrane fusion protein SNAP-23; synaptosomal-associated protein 23; synaptosomal-associated protein, 23kD; synaptosomal-associated protein, 23kDa. |
Gene ID : | 8773 |
mRNA Refseq : | NM_003825.2 |
Protein Refseq : | NP_003816.2 |
MIM : | 602534 |
UniProt ID : | O00161 |
Chromosome Location : | 15q15.1-q15.2 |
Pathway : | SNARE interactions in vesicular transport; Membrane Trafficking. |
Function : | protein binding. |
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◆ Lysates | ||
SNAP23-1641HCL | Recombinant Human SNAP23 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIn neurodegenerative diseases such as Alzheimer's disease, the expression level of SNAP23 may be reduced, which may affect the release of neurotransmitters and nerve signaling.
SNAP23 may influence neuronal death by regulating the fusion of synaptic vesicles and the release of neurotransmitters. Studies have shown that reducing the expression level of SNAP23 may increase the risk of neuronal death.
Recent studies have found that SNAP23 is associated with neuroinflammation. The level of expression of SNAP23 may affect the intensity and extent of the inflammatory response.
The interaction between SNAP23 and other proteins is regulated by the formation of complexes or the modulation of signal transduction pathways. These interactions can be influenced by a variety of factors, such as ion concentrations, neurotransmitters, and growth factors.
Recent studies have found that SNAP23 plays an important role in neurodegenerative diseases such as Alzheimer's disease. The study also found that SNAP23 expression levels were associated with neuroinflammation and neuronal death.
In addition to being involved in nerve signaling and neuronal death, SNAP23 may have effects on the nervous system in other ways. For example, SNAP23 may be involved in processes such as synaptic plasticity and learning and memory.
Customer Reviews (3)
Write a reviewThe pharmacodynamic parameters of SNAP23 were better.
SNAP23 has a strong desensitization potential to specific allergens.
SNAP23 has good compatibility and stability with various excipients.
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