Native Human Factor XIIIa was purified from Human plasma.
Human Factor XIIIa is activated from Factor XIII by cleavage with human alpha thrombin. The thrombin is subsequently removed via chromatography. Factor XIIIa is responsible for catalyzing the formation of covalent bridges between fibrin units to increase the elasticity of the clot network. The resulting cross-linked fibrin is very insoluble and resistant to lysis.
0.05M Tris-HCl; 0.1M NaCl; 0.001M EDTA; 10 U/ml Aprotinin; 0.05mM DTT; 50% Glycerol; pH 7.5
>95% by SDS-PAGE analysis
store at -20 centigrade.