Native Human MMP-1

• Cat.No.: MMP1-45H
• Product Overview: Matrix Metalloproteinase 1 (human interstitial collagenase, EC 3.4.24.7) prepared from human fibroblasts.

Specification

• Source: Human fibroblasts
• Species: Human
• Form: Liquid, in 50 mM Tris/HCl, pH 7.0, 300 mM NaCl, 5 mM CaCl2, 1 μM ZnCl2, 0.05% NaN3, 0.05% Brij 35
• Purity: >90%, homogenous by SDS-PAGE and Western Blotting analysis

Gene Information

• Gene Name: MMP1 matrix metallopeptidase 1 (interstitial collagenase) [ Homo sapiens ]
• Official Symbol: MMP1
• Synonyms: MMP1; matrix metallopeptidase 1 (interstitial collagenase); CLG, matrix metalloproteinase 1 (interstitial collagenase); interstitial collagenase; fibroblast collagenase; matrix metalloprotease 1; matrix metalloproteinase 1; CLG; CLGN
• Gene ID: 4312
• mRNA Refseq: NM_001145938
• Protein Refseq: NP_001139410
• MIM: 120353
• UniProt ID: P03956
• Chromosome Location: 11q21-q22
• Pathway: Activation of Matrix Metalloproteinases, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Basigin interactions, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem
• Function: calcium ion binding; metalloendopeptidase activity; peptidase activity; zinc ion binding