Recombinant Mouse Uchl1, His-tagged

• Cat.No.: Uchl1-69M
• Product Overview: Recombinant mouse Uchl1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: Uchl1 also known as Ubiquitin carboxyl-terminal hydrolase isozyme L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. UCHL1 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities.
• Source: E.coli
• Species: Mouse
• Tag: His
• Form: Liquid. In Phosphate buffered saline containing 10% glycerol, 1mM DTT
• Molecular Mass: 27.2kDa (246aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMQLKPME INPEMLNKVL AKLGVAGQWR FADVLGLEEE TLGSVPSPAC ALLLLFPLTA QHENFRKKQI EELKGQEVSP KVYFMKQTIG NSCGTIGLIH AVANNQDKLE FEDGSVLKQF LSETEKLSPE DRAKCFEKNE AIQAAHDSVA QEGQCRVDDK VNFHFILFNN VDGHLYELDG RMPFPVNHGA SSEDSLLQDA AKVCREFTER EQGEVRFSAV ALCKAA
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: Uchl1 ubiquitin carboxy-terminal hydrolase L1 [ Mus musculus ]
• Official Symbol: Uchl1
• Synonyms: UCHL1; ubiquitin carboxy-terminal hydrolase L1; ubiquitin carboxyl-terminal hydrolase isozyme L1; UCH-L1; PGP 9.5; gracile axonal dystrophy; protein gene product 9.5; ubiquitin thioesterase L1; neuron cytoplasmic protein 9.5; gad; C88048; PGP9.5; R75593; AW822034
• Gene ID: 22223
• mRNA Refseq: NM_011670
• Protein Refseq: NP_035800
• Pathway: Parkinsons disease, organism-specific biosystem
• Function: alpha-2A adrenergic receptor binding; cysteine-type endopeptidase activity; cysteine-type peptidase activity; hydrolase activity; ligase activity; omega peptidase activity; peptidase activity; ubiquitin binding; ubiquitin binding; ubiquitin thiolesterase activity