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Recombinant Mouse Tpt1, His-tagged

Cat.No. : Tpt1-70M
Product Overview : Recombinant mouse Tpt1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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Description : Tpt1 also known as Translationally-controlled tumor protein. TPT1 is regulated at the translational level. This protein is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients.
Source : E.coli
Species : Mouse
Tag : His
Form : Liquid. In Phosphate Buffered Saline containing 10% glycerol, 1mM DTT
Molecular Mass : 22.1kDa (197aa) confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSHMMIIYR DLISHDELFS DIYKIREIAD GLCLEVEGKM VSRTEGAIDD SLIGGNASAE GPEGEGTEST VVTGVDIVMN HHLQETSFTK EAYKKYIKDY MKSLKGKLEE QKPERVKPFM TGAAEQIKHI LANFNNYQFF IGENMNPDGM VALLDYREDG VTPFMIFFKD GLEMEKC
Purity : >90% by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 1mg/ml (determined by Bradford assay)
Gene Name : Tpt1 tumor protein, translationally-controlled 1 [ Mus musculus ]
Official Symbol : Tpt1
Synonyms : TPT1; tumor protein, translationally-controlled 1; translationally-controlled tumor protein; fortilin; translationally regulated transcript (21 kDa); 21 kDa polypeptide under translational control; Trt; p21; p23; TCTP;
Gene ID : 22070
mRNA Refseq : NM_009429
Protein Refseq : NP_033455
Function : calcium ion binding; transcription factor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the association between TPT1 and tumorigenesis? 06/02/2022

It is highly expressed in a variety of tumors, which is related to the occurrence and progression of tumors. Studies have shown that TPT1 may be involved in processes such as cell cycle regulation, apoptosis, and DNA repair.

How does TPT1 interact with other molecules or drugs? 05/04/2022

There are multiple interactions between TPT1 and other molecules and drugs. For example, TPT1 can bind to certain signaling molecules, which can affect the growth and differentiation of cells. In addition, some drugs can also affect TPT1 expression levels or function.

What are the treatments for TPT1? 05/08/2021

There is currently no specific treatment for TPT1. However, drugs that target their associated signal transduction pathways or binding targets may have potential therapeutic value.

Can TPT1 expression levels be used as a biomarker for tumor diagnosis or prognosis? 01/01/2021

At present, the expression level of TPT1 as a biomarker for tumor diagnosis or prognosis is not sufficient, and further validation is needed.

How can I detect TPT1 expression levels? 11/13/2020

TPT1 expression levels can be detected by gene sequencing, immunohistochemistry, and western blotting.

Are there have possible aspects of future research on TPT1? 05/05/2020

Future research on TPT1 may involve more in-depth molecular mechanism research, new drug development, and TPT1-based targeted therapy strategies. In addition, research may also address the function and mechanism of action of TPT1 in other tissues and organs.

Customer Reviews (3)

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Reviews
03/16/2022

    The quality is very good, the experimental effect is as expected, will continue to use.

    06/27/2021

      The product has reliable and stable performance, and is suitable for scientific research.

      08/28/2020

        We are reassured that their TPT1 quality is consistent.

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