Recombinant Human UBE2E3, His-tagged
Cat.No. : | UBE2E3-112H |
Product Overview : | Recombinant human UBE2E3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | UBE2E3 also known as Ubiquitin-conjugating enzyme E2 E3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. The ubiquitination process covalently attaches ubiquitin, a short protein of 76 amino acids, to a lysine residue on the target protein. Once a protein has been tagged with one ubiquitin molecule, additional rounds of ubiquitination form a polyubiquitin chain that is recognized by the proteasome"s 19S regulatory particle, triggering the ATP-dependent unfolding of the target protein that allows passage into the proteasome"s 20S core particle, where proteases degrade the target into short peptide fragments for recycling by the cell. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Liquid, In Phosphate buffered saline (pH7.4) containing 20% glycerol, 1mM DTT |
Molecular Mass : | 25.3kDa (230aa), confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMSSDRQR SDDESPSTSS GSSDADQRDP AAPEPEEQEE RKPSATQQKK NTKLSSKTTA KLSTSAKRIQKELAEITLDP PPNCSAGPKG DNIYEWRSTI LGPPGSVYEG GVFFLDITFS SDYPFKPPKV TFRTRIYHCN INSQGVICLD ILKDNWSPAL TISKVLLSIC SLLTDCNPAD PLVGSIATQY LTNRAEHDRI ARQWTKRYAT |
Purity : | >80% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by Bradford assay) |
Gene Name : | UBE2E3 ubiquitin-conjugating enzyme E2E 3 [ Homo sapiens ] |
Official Symbol : | UBE2E3 |
Synonyms : | UBE2E3; ubiquitin-conjugating enzyme E2E 3; ubiquitin conjugating enzyme E2E 3 (homologous to yeast UBC4/5) , ubiquitin conjugating enzyme E2E 3 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2 E3; UbcH9; ubiquitin-protein ligase E3; ubiquitin carrier protein E3; ubiquitin-conjugating enzyme E2-23 kDa; ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5); UBCH9; UbcM2; |
Gene ID : | 10477 |
mRNA Refseq : | NM_006357 |
Protein Refseq : | NP_006348 |
MIM : | 604151 |
UniProt ID : | Q969T4 |
Chromosome Location : | 2q31.3 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; |
Function : | ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; ubiquitin-protein ligase activity; |
Products Types
◆ Recombinant Protein | ||
UBE2E3-0027H | Recombinant Human UBE2E3 Protein (S2-T207), Tag Free | +Inquiry |
UBE2E3-0028H | Recombinant Human UBE2E3 Protein (S2-T207), His/Strep tagged | +Inquiry |
UBE2E3-4871R | Recombinant Rhesus Macaque UBE2E3 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2E3-5058R | Recombinant Rhesus monkey UBE2E3 Protein, His-tagged | +Inquiry |
UBE2E3-31658TH | Recombinant Human UBE2E3 | +Inquiry |
◆ Lysates | ||
UBE2E3-580HCL | Recombinant Human UBE2E3 293 Cell Lysate | +Inquiry |
UBE2E3-581HCL | Recombinant Human UBE2E3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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