Recombinant Human LCK, MYC/DDK-tagged
Cat.No. : | LCK-273H |
Product Overview : | Recombinant Human LCK, transcript variant 2, fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. |
Source : | HEK293 cells |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 57.8 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | LCK LCK proto-oncogene, Src family tyrosine kinase [ Homo sapiens ] |
Official Symbol : | LCK |
Synonyms : | LSK; YT16; IMD22; p56lck; pp58lck; tyrosine-protein kinase Lck; T-lymphocyte specific protein tyrosine kinase p56lck; leukocyte C-terminal Src kinase; lymphocyte cell-specific protein-tyrosine kinase; lymphocyte-specific protein tyrosine kinase; p56(LSTRA) protein-tyrosine kinase; proto-oncogene tyrosine-protein kinase LCK; t cell-specific protein-tyrosine kinase |
Gene ID : | 3932 |
mRNA Refseq : | NM_005356 |
Protein Refseq : | NP_005347 |
MIM : | 153390 |
UniProt ID : | P06239 |
Chromosome Location : | 1p34.3 |
Pathway : | Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem |
Function : | ATP binding; ATPase binding; SH2 domain binding |
Products Types
◆ Recombinant Protein | ||
LCK-174H | Recombinant Human LCK Protein (SH3 Domain), GST tagged | +Inquiry |
LCK-3021R | Recombinant Rat LCK Protein, His (Fc)-Avi-tagged | +Inquiry |
Lck-1300M | Recombinant Mouse Lck Protein, MYC/DDK-tagged | +Inquiry |
LCK-29218TH | Recombinant Human LCK | +Inquiry |
LCK-173H | Active Recombinant Human LCK | +Inquiry |
◆ Lysates | ||
LCK-681HCL | Recombinant Human LCK cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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