Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human MSH3 Protein, His-tagged

Cat.No. : MSH3-494H
Product Overview : Recombinant human MSH3 protein with a His-tag was expressed in E. coli
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.
Source : E. coli
Species : Human
Tag : His
Molecular Mass : The protein has a calculated MW of 40.3 kDa.
AA Sequence : MGSSHHHHHHSSGLVPRGSHMSRRK PASGGLAASSSAPARQAVLSRFFQS TGSLKSTSSSTGAADQVDPGAAAAA AAAAATAPPAPPAPAFPPQLPPHIA TEIDRRKKRPLENDGPVKKKVKKVQ QKEGGSDLGMSGNSEPKKCLRTRNV SKSLEKLKEFCCDSALPQSRVQTES LQERFAVLPKCTDFDDISLLHAKNA VSSEDSKRQINQKDTTLFDLSQFGS SNTSHENLQKTASKSANKRSKSIYT PLELQYIEMKQQHKDAVLCVECGYK YRFFGEDAEIAARELNIYCHLDHNF MTASIPTHRLFVHVRRLVAKGYKVG VVKQTETAALKAIGDNRSSLFSRKL TALYTKSTLIGEDVNPLIKL
Endotoxin : <1 EU/μg
Purity : >85% by SDS-PAGE
Storage : Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Lyophilized from sterile PBS, Ph7.4, 5% trehalose, 5% mannitol added with 0.25M Arginine
Gene Name : MSH3 mutS homolog 3 (E. coli) [ Homo sapiens (human) ]
Official Symbol : MSH3
Synonyms : MSH3; mutS homolog 3 (E. coli); mutS (E. coli) homolog 3; DNA mismatch repair protein Msh3; Divergent upstream protein; DUP; Mismatch repair protein 1; MRP1; hMSH3; mismatch repair protein 1; divergent upstream protein; MGC163306; MGC163308;
Gene ID : 4437
mRNA Refseq : NM_002439
Protein Refseq : NP_002430
MIM : 600887
UniProt ID : P20585

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All MSH3 Products

Required fields are marked with *

My Review for All MSH3 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends