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Recombinant Human ARSI lysate

Cat.No. : ARSI-39HCL
Product Overview : Over-expression cells lysed in RIPA buffer and lysate supplied in SDS loading buffer
  • Specification
  • Gene Information
  • Related Products
Source : HEK 293 cells
Species : Human
Molecular Mass : 66529.79Da
Recommended Usage : WB
Storage Instruction : Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Gene Name : ARSI arylsulfatase family, member I [ Homo sapiens ]
Official Symbol : ARSI
Synonyms : ARSI; arylsulfatase family, member I; arylsulfatase I; FLJ16069; ASI;
Gene ID : 340075
mRNA Refseq : NM_001012301
Protein Refseq : NP_001012301
MIM : 610009
UniProt ID : Q5FYB1
Chromosome Location : 5q32
Function : arylsulfatase activity; hydrolase activity; metal ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Can autosomal recessive multiple sulfatase deficiency be prevented? 11/22/2021

Autosomal recessive multiple sulfatase deficiency is a genetic disorder that results from inherited mutations, so it cannot be prevented at present. However, genetic counseling and testing can help identify carrier status in individuals and guide family planning decisions.

Are there any ongoing research efforts for autosomal recessive multiple sulfatase deficiency? 08/11/2021

Yes, research is ongoing to better understand the underlying mechanisms of autosomal recessive multiple sulfatase deficiency and to develop potential treatments. This includes studying enzyme replacement therapy, gene therapy, and other innovative approaches.

How is autosomal recessive multiple sulfatase deficiency diagnosed? 06/09/2020

Diagnosis of autosomal recessive multiple sulfatase deficiency is typically confirmed through clinical evaluation, examination of symptoms, and genetic testing to identify ARSI gene mutations.

What are some examples of molecules that the ARSI protein acts upon? 12/29/2019

The ARSI protein acts on various molecules, including glycosaminoglycans (GAGs) such as heparan sulfate, chondroitin sulfate, and dermatan sulfate. It also acts on sulfated steroids like estrone sulfate and dehydroepiandrosterone sulfate.

What are the symptoms of autosomal recessive multiple sulfatase deficiency? 04/12/2019

Symptoms of autosomal recessive multiple sulfatase deficiency can vary but may include developmental delays, intellectual disability, skeletal abnormalities, skin abnormalities, and in severe cases, organ dysfunction.

Can individuals with autosomal recessive multiple sulfatase deficiency have children? 02/05/2019

Autosomal recessive multiple sulfatase deficiency is a rare and severe disorder, and individuals with the condition typically experience significant health challenges. In most cases, affected individuals may have difficulty having children due to their overall health condition and associated complications. However, family planning decisions should be discussed with healthcare professionals based on individual circumstances.

Can you explain the impact of ARSI protein malfunction on sulfate metabolism? 11/13/2018

When the ARSI protein is deficient or non-functional, the removal of sulfate groups from molecules is impaired. This leads to the accumulation of sulfated compounds within cells, disrupting their normal function and potentially causing downstream effects on various biological processes.

Is there a treatment for autosomal recessive multiple sulfatase deficiency? 02/08/2018

There is currently no cure for autosomal recessive multiple sulfatase deficiency, and treatment primarily focuses on managing symptoms and providing supportive care. This may include physical therapy, occupational therapy, and medical interventions to address specific symptoms or complications.

What happens if the ARSI protein is deficient or non-functional? 09/16/2017

Deficiency or non-functioning of the ARSI protein can result in a condition known as autosomal recessive multiple sulfatase deficiency (MSD). This condition leads to the accumulation of sulfated molecules within cells, causing a variety of symptoms throughout the body.

Are there any other proteins or enzymes involved in sulfate metabolism? 08/26/2017

Yes, there are other proteins and enzymes involved in sulfate metabolism. For example, the ARSJ protein (Arylsulfatase J) is another enzyme that plays a role in removing sulfate groups. Additionally, proteins involved in sulfate transport, such as SLC13A1 and SLC26A2, are important for maintaining sulfate balance within cells.

Customer Reviews (3)

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Reviews
08/01/2020

    Whether I am studying protein-protein interactions, investigating cellular pathways, or examining protein folding dynamics, the ARSI protein consistently delivers exceptional performance and precise outcomes.

    01/22/2018

      The versatility of the ARSI protein is truly remarkable, as it can be employed across a wide range of applications in my research.

      04/11/2016

        The excellent technical support provided by the manufacturer can solve my problem.

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