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Recombinant Human SIRT1 lysate

Cat.No. : SIRT1-595HCL
Product Overview : Over-expression cells lysed in RIPA buffer and lysate supplied in SDS loading buffer
  • Specification
  • Gene Information
  • Related Products
Source : HEK 293 cells
Species : Human
Molecular Mass : 61886.16Da
Recommended Usage : WB
Storage Instruction : Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Gene Name : SIRT1 sirtuin 1 [ Homo sapiens ]
Official Symbol : SIRT1
Synonyms : SIRT1; sirtuin 1; sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) , sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1; NAD-dependent deacetylase sirtuin-1; SIR2L1; hSIR2; hSIRT1; SIR2alpha; sir2-like 1; sirtuin type 1; SIR2-like protein 1;
Gene ID : 23411
mRNA Refseq : NM_001142498
Protein Refseq : NP_001135970
MIM : 604479
UniProt ID : Q96EB6
Chromosome Location : 10q21
Pathway : Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; E2F transcription factor network, organism-specific biosystem; Energy Metabolism, organism-specific biosystem; FoxO family signaling, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem; Regulation of Androgen receptor activity, organism-specific biosystem;
Function : HLH domain binding; NOT NAD+ ADP-ribosyltransferase activity; NAD+ binding; NAD-dependent histone deacetylase activity; NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent protein deacetylase activity; NAD-dependent protein deacetylase activity; bHLH transcription factor binding; deacetylase activity; enzyme binding; histone binding; histone deacetylase activity; identical protein binding; metal ion binding; mitogen-activated protein kinase binding; p53 binding; protein C-terminus binding; protein binding; protein deacetylase activity; transcription corepressor activity; transcription corepressor activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Does SIRT1 play a role in tissue regeneration? 10/13/2022

Studies have found that SIRT1 plays an important role in tissue regeneration. Activation of SIRT1 can promote the proliferation and differentiation of stem cells, which contributes to tissue regeneration and repair.

Is SIRT1 related to autophagy? 08/31/2021

Activation of SIRT1 promotes autophagy, which helps to remove damaged organelles and proteins and maintain cell health.

What is the relationship between SIRT1 and mitochondrial function? 01/19/2021

SIRT1 regulates mitochondrial function. Activation of SIRT1 can improve mitochondrial metabolism and function, contributing to energy metabolism and cell survival.

What role does SIRT1 play in cancer? 07/21/2020

Studies have found that SIRT1 exerts carcinogenic effects in some cancers, but exerts anti-cancer effects in others. It depends on the type of cancer and environmental factors.

What is the potential of SIRT1 in drug development? 05/20/2020

SIRT1 has potential therapeutic value in drug development. The development of small molecule drugs targeting SIRT1 can be used to treat a variety of diseases, including aging, diabetes, cardiovascular diseases, and neurodegenerative diseases.

How does SIRT1 relate to other sirtuins? 01/08/2020

SIRT1 interacts and regulates with other sirtuins. For example, SIRT1 can regulate the expression and activity of other Sirtuins, and other Sirtuins can also regulate the activity of SIRT1.

Customer Reviews (3)

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Reviews
10/12/2021

    Resulting banding is clear and bright, much more than expected.

    10/09/2021

      SIRT1 has high safety, environmental protection and no pollution.

      01/03/2021

        The quality is so good. It saves a lot of time. Good.

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