S Cellulose resin

• Cat.No.: Methylsulphonate-003C
• Product Overview: S strong ion exchangers are highly cross-linked, surface modified media with high dynamic binding capacities and stable at high flow velocities. These high performances of the optimized media offer significant opportunity for increasing downstream purification throughput.

Specification

• Cat.no: Methylsulphonate-003C
• Matrix: Highly cross-linked cellulose with dextran scaffold
• Ion exchange capacity: 0.13-0.25 meq /ml
• Functional group: Methylsulphonate: -CH2SO3–
• Protein: Methylsulphonate
• Average particle size: 40 – 130 um
• Dynamic binding capacity: >130mg IgG/ml gel
• Recommended flow rate: 1,000 cm/h in a 2.2cm diameter column with 20cm bed height at<>Over 500cm/h 30cm diameter column with 20cm bed height at<>
• Viscosity: Store unopened container at ambient temperature. Do not freeze.Short-term storage for bulk and column (2 weeks or less) can be at a room temperature with pH 2 to pH 14. It is possible to store under alkaline condition at less than 20°C as recommendation.0.1M NaOH ; 2-4 months0.5M NaOH ; less than 1 monthLonger storage should be in neutral buffer containing 20 % ethanol, at 2 – 8 °C. Do not freeze.
• Chemical stability: Stable in:Most salts (NaCl, (NH4)2SO4, etc.), Alcohol ( 30 % (v/v) IPA, 70 % (v/v) EtOH), Urea (6M) and Guanidine-HCl (6M); pH 2 to pH14 (MAX S-r) , pH3 to pH14 (MAX S-h) at 40oC,1 week 0.1M NaOH at less than 20oC, 3 months (MAX S-r & S-h)
• Physical stability: Stable in:Most salts (NaCl, (NH4)2SO4, etc.), Alcohol ( 30 % (v/v) IPA, 70 % (v/v) EtOH), Urea (6M) and Guanidine-HCl (6M); pH 2 to pH14 (MAX S-r) , pH3 to pH14 (MAX S-h) at 40oC,1 week 0.1M NaOH at less than 20oC, 3 months (MAX S-r & S-h)
• pH working range: 2 – 13
• pH CIP range: 3 - 14
• Elution buffer: 0.1 – 2.0 M sodium chloride in adsorption buffer