Native Bovine PTI therapeutic protein

• Cat.No.: PTI-P063B
• Product Overview: Bovine pancreatic trypsin inhibitor therapeutic protein?is a protein, that is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. Its main effect is the slowing down of fibrinolysis, the process that leads to the breakdown of blood clots. The aim in its use is to decrease the need for blood transfusions during surgery, as well as end-organ damage due to hypotension (low blood pressure) as a result of marked blood loss.

Specification

• Description: Our expression product is the active ingredient of Trasylol and Aprotinin.
• Species: Bovine
• Molecular Mass: 6.51 Kda
• Protein length: 58 Aa
• AA Sequence: RPDFCLEPPYTGPCKARIIRYFYNA KAGLCQTFVYGGCRAKRNNFKSAED CMRTCGGA
• Endotoxin: < 1.0 EU per μg of the protein
• Purity: >95%
• Storage: Can be stored at +4 centigrade short term (1-2weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoidrepeated freezing and thawing cycles.

Gene Information

• Gene Name: PTI pancreatic trypsin inhibitor [ Bos taurus ]
• Official Symbol: PTI
• Synonyms: BPI; BPTI; aprotinin; basic protease inhibitor
• Gene ID: 404172
• mRNA Refseq: NM_001001554
• Protein Refseq: NP_001001554
• Chromosome Location: chromosome: 13
• Function: potassium channel inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity