Active Recombinant Mouse Wnt3a
| Cat.No. : | Wnt3a-180M |
| Product Overview : | Recombinant Mouse Wnt3a was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
| Description : | Wnt-3a signalling has been implicated in the control of differentiation of stem cells. Wnt proteins have been shown to regulate cell-to-cell interactions during embryogenesis, more specifically regulating mesoderm differentiation and osteogenesis. The Wnts have also been shown to have putative roles in the regulation of adult stem cells. Recombinant murine Wnt-3a is active in human cells. Recombinant murine Wnt-3a is a monomeric glycoprotein. Murine Wnt-3a migrates at an apparent molecular weight of approximately 35 kDa. |
| Source : | Insect cells |
| Species : | Mouse |
| Form : | Colourless liquid. |
| Bio-activity : | ED50 of Wnt-3a is 12.5 - 25 ng/ml as determined by assay of mouse mammary epithelial cells (Eph4) with a TCF-fluorescent reporter. |
| Molecular Mass : | 35 kDa |
| Protein length : | 328 a.a. |
| Endotoxin : | Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug. |
| Purity : | >70% |
| Stability : | Wnt-3a is stable for at least 6 months when stored at -20ºC. Store long term at -80ºC. Withstands at least one freeze-thaw cycle. Aliquot before use. |
| Storage : | -20ºC |
| Storage Buffer : | Centrifuge vial before opening. Supplied at a concentration of 20 ug/ml in phosphate buffered saline with 1% BSA, 0.1M NaCl and 1% CHAPS. |
| Gene Name : | Wnt3a wingless-type MMTV integration site family, member 3A [ Mus musculus (house mouse) ] |
| Official Symbol : | Wnt3a |
| Synonyms : | Wnt3a; vt; Wnt-3a; wingless-type MMTV integration site family, member 3A; protein Wnt-3a; vestigial tail; wingless-related MMTV integration site 3A |
| Gene ID : | 22416 |
| mRNA Refseq : | NM_009522 |
| Protein Refseq : | NP_033548 |
| UniProt ID : | P27467 |
| Chromosome Location : | 11 B1.3; 11 37.17 cM |
| Pathway : | Basal cell carcinoma; Class B/2 (Secretin family receptors); Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) |
| Function : | frizzled binding; frizzled-2 binding; protein binding; protein domain specific binding |
Products Types
| ◆ Recombinant Protein | ||
| WNT3A-10196M | Recombinant Mouse WNT3A Protein, His (Fc)-Avi-tagged | +Inquiry |
| WNT3A-116H | Recombinant Human WNT3A Protein | +Inquiry |
| Wnt3a-56M | Active Recombinant Mouse Wnt3a Protein | +Inquiry |
| Wnt3a-585M | Recombinant Mouse Wnt3a Protein, His-tagged | +Inquiry |
| WNT3A-55H | Active Recombinant Human WNT3A Protein, Animal Free | +Inquiry |
| ◆ Lysates | ||
| WNT3A-295HCL | Recombinant Human WNT3A 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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