Recombinant Human Type II Topoisomerase, His-tagged
| Cat.No. : |
TOP2B-01H |
| Product Overview : |
Recombinant hTOP2βcore (residues 445-1201), fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
| Source : |
E.coli |
| Species : |
Human |
| Tag : |
His |
| Form : |
20 mM Tris-HCl, 200 mM NaCl, pH7.4 |
| Molecular Mass : |
~87 kDa |
| AA Sequence : |
SVKYSKIKGIPKLDDANDAGGKHSL ECTLILTEGDSAKSLAVSGLGVIGR DRYGVFPLRGKILNVREASHKQIME NAEINNIIKIVGLQYKKSYDDAESL KTLRYGKIMIMTDQDQDGSHIKGLL INFIHHNWPSLLKHGFLEEFITPIV KASKNKQELSFYSIPEFDEWKKHIE NQKAWKIKYYKGLGTSTAKEAKEYF ADMERHRILFRYAGPEDDAAITLAF SKKKIDDRKEWLTNFMEDRRQRRLH GLPEQFLYGTATKHLTYNDFINKEL ILFSNSDNERSIPSLVDGFKPGQRK VLFTCFKRNDKREVKVAQLAGSVAE MSAYHHGEQALMMTIVNLAQNFVGS NNINLLQPIGQFGTRLHGGKDAASP RYIFTMLSTLARLLFPAVDDNLLKF LYDDNQRVEPEWYIPIIPMVLINGA EGIGTGWACKLPNYDAREIVNNVRR MLDGLDPHPMLPNYKNFKGTIQELG QNQYAVSGEIFVVDRNTVEITELPV RTWTQVYKEQVLEPMLNGTDKTPAL ISDYKEYHTDTTVKFVVKMTEEKLA QAEAAGLHKVFKLQTTLTCNSMVLF DHMGCLKKYETVQDILKEFFDLRLS YYGLRKEWLVGMLGAESTKLNNQAR FILEKIQGKITIENRSKKDLIQMLV QRGYESDPVKAWKEAQEKAAEEDET QNQHDDSSSDSGTPSGPDFNYILNM SLWSLTKEKVEELIKQRDAKGREVN DLKRKSPSDLWKEDLAAFVEELDKV ESQERED |
| Purity : |
>92% as determined by SDS-PAGE |
| Storage : |
Short Term Storage at +4°C. Long Term Storage at -20°C to -80°C. Avoid freeze/thaw cycles. |
| Gene Name : |
TOP2B topoisomerase (DNA) II beta 180kDa [ Homo sapiens ] |
| Official Symbol : |
TOP2B |
| Synonyms : |
TOP2B; topoisomerase (DNA) II beta 180kDa; topoisomerase (DNA) II beta (180kD); DNA topoisomerase 2-beta; topo II beta; antigen MLAA-44; topoisomerase IIb; topoisomerase II beta; U937 associated antigen; DNA topoisomerase II beta; DNA topoisomerase II, 180 kD; DNA topoisomerase II, beta isozyme; TOPIIB; top2beta; |
| Gene ID : |
7155 |
| mRNA Refseq : |
NM_001068 |
| Protein Refseq : |
NP_001059 |
| MIM : |
126431 |
| UniProt ID : |
Q02880 |
| Chromosome Location : |
3p24 |
| Function : |
ATP binding; DNA topoisomerase (ATP-hydrolyzing) activity; DNA-dependent ATPase activity; chromatin binding; enzyme binding; histone deacetylase binding; isomerase activity; nucleotide binding; protein C-terminus binding; protein heterodimerization activity; protein kinase C binding; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
