Recombinant Human HAMP, MYC/DDK-tagged
Cat.No. : | HAMP-12H |
Product Overview : | Recombinant Human HAMP, fused with C-terminal MYC/DDK, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. |
Source : | HEK293 cells |
Species : | Human |
Tag : | MYC/DDK |
Molecular Mass : | 6.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | HAMP hepcidin antimicrobial peptide [ Homo sapiens (human) ] |
Official Symbol : | HAMP |
Synonyms : | HAMP; hepcidin antimicrobial peptide; HEPC; PLTR; HFE2B; LEAP1; hepcidin; liver-expressed antimicrobial peptide 1; putative liver tumor regressor |
Gene ID : | 57817 |
mRNA Refseq : | NM_021175 |
Protein Refseq : | NP_066998 |
UniProt ID : | P81172 |
Chromosome Location : | 19q13.1 |
Pathway : | Iron metabolism in placenta |
Function : | hormone activity |
Products Types
◆ Recombinant Protein | ||
Hamp-3354M | Recombinant Mouse Hamp Protein, Myc/DDK-tagged | +Inquiry |
HAMP-955H | Recombinant Human HAMP Protein, His-tagged | +Inquiry |
HAMP-2732D | Recombinant Dog HAMP Protein, His&GST-tagged | +Inquiry |
HAMP-4564H | Recombinant Human HAMP Protein, GST-tagged | +Inquiry |
HAMP-2268L | Recombinant Larimichthys Crocea HAMP Protein (65-85 aa) | +Inquiry |
◆ Lysates | ||
HAMP-5640HCL | Recombinant Human HAMP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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