"GH1" Related Products

Expand
Expand

Human GH1 Stable Cell Line-E. coli

Cat.No.: CSC-TP077
Product Overview: E.coli-Human Growth Hormone Stable Cell Line(Somatropin) is clonally-derived from a E.coli cell line, which has been transfected with an GH gene to allow expression of Human Growth Hormone.
Description: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. The expression product is the active ingredient of BioTropin, Genotropin, Humatrope, Norditropin, Nutropin, NutropinAQ, Protropin, Saizen, Serostim and Tev-Tropin.
Source: E. coli
Species: Human
Molecular Mass: 22.1KDa
Protein length: 191 Aa
Endotoxin: < 1.0 EU per μg of the protein
Purity: >95%
Notes: Growth Properties: Suspension;
Morphology: Epithelial-like.
Storage: Can be stored at +4 centigrade short term (1-2weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoidrepeated freezing and thawing cycles.
Gene Name: GH1 growth hormone 1 [ Homo sapiens ]
Official Symbol: GH1
Synonyms: GH1; growth hormone 1; somatotropin; GH; GH N; GHN; hGH N; pituitary growth hormone; GH-N; hGH-N; IGHD1B;
Gene ID: 2688
mRNA Refseq: NM_000515
Protein Refseq: NP_000506
MIM: 139250
UniProt ID: P01241
Chromosome Location: 17q22-q24
Pathway: Adipogenesis, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem;
Function: growth factor activity; growth hormone receptor binding; growth hormone receptor binding; hormone activity; metal ion binding; prolactin receptor binding; protein binding;

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.