Recombinant Human DRD5

• Cat.No.: DRD5-12H
• Product Overview: Recombinant Human DRD5, fused without tag, was expressed in wheat germ.

Specification

• Description: This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2.
• Source: Wheat germ
• Species: Human
• Form: Liquid
• Molecular Mass: 52.47 kDa
• AA Sequence: MLPPGSNGTAYPGQFALYQQLAQGN AVGGSAGAPPLGPSQVVTACLLTLL IIWTLLGNVLVCAAIVRSRHLRANM TNVFIVSLAVSDLFVALLVMPWKAV AEVAGYWPFGAFCDVWVAFDIMCST ASILNLCVISVDRYWAISRPFRYKR KMTQRMALVMVGLAWTLSILISFIP VQLNWHRDQAASWGGLDLPNNLANW TPWEEDFWEPDVNAENCDSSLNRTY AISSSLISFYIPVAIMIVTYTRIYR IAQVQIRRISSLERAAEHAQSCRSS AACAPDTSLRASIKKETKVLKTLSV IMGVFVCCWLPFFILNCMVPFCSGH PEGPPAGFPCVSETTFDVFVWFGWA NSSLNPVIYAFNADFQKVFAQLLGC SHFCSRTPVETVNISNELISYNQDI VFHKEIAAAYIHMMPNAVTPGNREV DNDEEEGPFDRMFQIYQTSPDGDPV AESVWELDCEGEISLDKITPFTPNG FH
• Applications: Antibody Production; Functional Study; Compound Screening
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80ºC. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: DRD5 dopamine receptor D5 [ Homo sapiens (human) ]
• Official Symbol: DRD5
• Synonyms: DRD5; dopamine receptor D5; DBDR; DRD1B; DRD1L2; D(1B) dopamine receptor; D1beta dopamine receptor; d(5) dopamine receptor; dopamine D5 receptor; dopamine receptor D1B
• Gene ID: 1816
• mRNA Refseq: NM_000798
• Protein Refseq: NP_000789
• MIM: 126453
• UniProt ID: P21918
• Chromosome Location: 4p16.1
• Pathway: Amine ligand-binding receptors; Calcium signaling pathway; Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
• Function: G-protein coupled amine receptor activity; dopamine binding; dopamine neurotransmitter receptor activity