Recombinant Human CES2, MYC/DDK-tagged
Cat.No. : | CES2-1141H |
Product Overview : | Recombinant Human CES2, fused with C-terminal MYC/DDK, was expressed in HEK293 Cells. |
- Specification
- Gene Information
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Source : | HEK293 cells |
Species : | Human |
Tag : | MYC/DDK |
Molecular Mass : | 68.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | CES2 carboxylesterase 2 [ Homo sapiens (human) ] |
Official Symbol : | CES2 |
Synonyms : | CES2; carboxylesterase 2; iCE; CE-2; PCE-2; CES2A1; cocaine esterase; carboxylesterase 2 (intestine, liver); hCE-2; intestinal carboxylesterase; liver carboxylesterase-2; methylumbelliferyl-acetate deacetylase 2; NP_003860.2; EC 3.1.1.1; EC 3.1.1.56; EC 3.1.1.84; NP_932327.1 |
Gene ID : | 8824 |
mRNA Refseq : | NM_003869 |
Protein Refseq : | NP_003860 |
MIM : | 605278 |
UniProt ID : | O00748 |
Chromosome Location : | 16q22.1 |
Pathway : | Drug metabolism - other enzymes; E2F transcription factor network; Fluoropyrimidine Activity; Phase I, non P450 |
Function : | carboxylic ester hydrolase activity; methylumbelliferyl-acetate deacetylase activity |
Products Types
◆ Recombinant Protein | ||
CES2-22H | Active Recombinant Human CES2 Protein, His-tagged | +Inquiry |
CES2-749H | Recombinant Human CES2 Protein, His-tagged | +Inquiry |
CES2-1149H | Recombinant Human CES2 Protein, GST-Tagged | +Inquiry |
CES2-107H | Active Recombinant Human CES2 Protein | +Inquiry |
CES2-2661H | Recombinant Human CES2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CES2-2139HCL | Recombinant Human CES2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCES2, a carboxylesterase enzyme, is crucial in metabolizing various drugs by hydrolyzing ester and amide bonds.
Genetic variations in CES2 can lead to differences in drug metabolism, influencing treatment outcomes.
CES2 collaborates with other metabolic enzymes, playing a role in the body's overall drug-processing capacity.
CES2 is involved in activating prodrugs in the intestine, affecting their absorption and therapeutic action.
Understanding CES2 activity could aid in developing personalized treatment plans, optimizing drug efficacy and safety.
Altered CES2 activity can significantly affect the pharmacokinetics of drugs, altering their efficacy and toxicity.
It helps in the breakdown of drugs, facilitating their conversion into active or inactive metabolites.
Customer Reviews (3)
Write a reviewExceptional support. Accelerates research timelines.
Critical for research integrity. Integral to experiments.
Timely and precise. Trusted for research milestones.
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