Recombinant Human ActRIIA therapeutic protein, Fc-tagged
| Cat.No. : | ACVR2A-P015H |
| Product Overview : | Recombinant Human ActRIIA fused with Fc protein of human IgG1 was expressed. |
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- Specification
- Gene Information
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| Species : | Human |
| Tag : | Fc |
| Endotoxin : | < 0.1 eu per μg of the protein |
| Purity : | >95% |
| Publication : |
Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and Western Single Blotting. (2017)
Combined detection of the ActRII‐Fc fusion proteins Sotatercept (ActRIIA‐Fc) and Luspatercept (modified ActRIIB‐Fc) in serum by means of immunoaffinity purification, tryptic digestion, and LC‐MS/MS (2018)
Updated protocols for the detection of Sotatercept and Luspatercept in human serum (2018)
Antibody-based strategies for the detection of Luspatercept (ACE-536) in human serum (2017)
Testing for the erythropoiesis-stimulating agent Sotatercept/ACE-011 (ActRIIA-Fc) in serum by means of Western blotting and LC-HRMS (2016)
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| Gene Name : | ACVR2A activin A receptor, type IIA [ Homo sapiens ] |
| Official Symbol : | ACVR2A |
| Synonyms : | ACVR2A; activin A receptor, type IIA; activin A receptor, type II , ACVR2; activin receptor type-2A; ACTRII; ACVR2; |
| Gene ID : | 92 |
| mRNA Refseq : | NM_001616 |
| Protein Refseq : | NP_001607 |
| MIM : | 102581 |
| UniProt ID : | P27037 |
| Chromosome Location : | 2q22.2-q23.3 |
| Pathway : | ALK1 signaling events, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Developmental Biology, organism-specific biosystem; Regulation of Signaling by NODAL, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem; |
| Function : | ATP binding; contributes_to activin binding; activin receptor activity, type II; contributes_to activin-activated receptor activity; coreceptor activity; growth factor binding; inhibin beta-A binding; inhibin beta-B binding; metal ion binding; nucleotide binding; protein binding; contributes_to protein binding; protein self-association; protein serine/threonine kinase activity; receptor activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity; |
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| ACVR2A-01H | Recombinant Active Human ACVR2A Protein, His-tagged | +Inquiry |
| ◆ Lysates | ||
| ACVR2A-3096HCL | Recombinant Human ACVR2A cell lysate | +Inquiry |
| ACVR2A-2280MCL | Recombinant Mouse ACVR2A cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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