Active Recombinant Cotton Rat Il2, Met-tagged
Cat.No. : | Il2-381C |
Product Overview : | Recombinant Cotton Rat Il2 (Accession # AAK94012) Ala21-Gln155 (Cys146Tyr), fused with an N-terminal Met, was produced in E. coli-derived. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Cotton Rat |
Predicted N Terminal : | Met & Ala21 |
Form : | Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein. |
Bio-activity : | Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. Gearing, A.J.H. and C.B. Bird (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 295.The ED50 for this effect is typically 0.15 - 0.6 ng/mL. |
Molecular Mass : | Recombinant Cotton Rat Il2, Met-tagged has a calculated MW of 15.6 kDa. |
Purity : | >97%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Reconstitution : | Reconstitute at 50 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Gene Name : | Il2 interleukin 2 [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Il2 |
Synonyms : | Il2; interleukin 2; interleukin-2; IL-2; T-cell growth factor; TCGF |
Gene ID : | 116562 |
mRNA Refseq : | NM_053836 |
Protein Refseq : | NP_446288 |
MIM : | |
UniProt ID : | P17108 |
Chromosome Location : | 2q25 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionIL2 promotes the formation of memory T-cells.
IL2 has a pro-tumorigenic role in the tumor microenvironment.
IL2 synergizes with IL-12 in a mixed cytokine environment.
IL2 upregulates the expression of PD-1 checkpoint inhibitors.
IL2 is rapidly internalized by activated T-cells.
IL2 induces M1 macrophage polarization.
IL2 increases blood-brain barrier permeability.
IL2's affinity for its receptor decreases under hypoxic conditions.
IL2's bioactivity is enhanced by glycosylation.
IL2 promotes the differentiation of Th17 cells.
Customer Reviews (3)
Write a reviewPotent in T-cell activation.
Suitable for cytokine assays.
High stability.
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