Active Recombinant Mouse Notch1, Fc Chimera

• Cat.No.: Notch1-400M
• Product Overview: Recombinant Mouse Notch1 (Accession # AAM28905) was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Source: CHO cells
• Species: Mouse
• Tag: Fc Chimera
• Predicted N Terminal: Ala19
• Form: Lyophilized from a 0.2 µm filtered solution in PBS and EDTA.
• Bio-activity: Measured by its binding ability in a functional ELISA.Immobilized Recombinant Mouse Notch-1 Fc Chimera at 2 µg/mL (100 µL/mL) can bind Recombinant Rat Jagged 1 Fc Chimera with an apparent KD < 2 nM.
• Molecular Mass: Recombinant Mouse Notch1, Fc Chimera has a calculated MW of 80.7 kDa (monomer). In SDS-PAGE migrates as 110-120 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Notch1 Notch gene homolog 1 (Drosophila) [ Mus musculus ]
• Official Symbol: Notch1
• Synonyms: NOTCH1; Notch gene homolog 1 (Drosophila); neurogenic locus notch homolog protein 1; mT14; p300; Motch A; notch 1; major type A protein; transmembrane receptor Notch1; N1; Mis6; Tan1; lin-12; 9930111A19Rik
• Gene ID: 18128
• mRNA Refseq: NM_008714
• Protein Refseq: NP_032740