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Active Recombinant Human PTK2B, His-tagged

Cat.No. : PTK2B-570H
Product Overview : Recombinant Human PTK2B (Accession # NM_004103) amino acids 360 - 690, fused with an N-terminal His tag, was produced in baculovirus in Sf 9 insect cells.
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  • Gene Information
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Source : Sf 9 insect cells
Species : Human
Tag : His
Form : Supplied in 50 mM sodium phosphate (pH 7.0), 300 mM NaCl, 0.2 mM DTT, 150 mM imidazole, 0.1 mM PMSF, and 25% glycerol.
Bio-activity : The specific activity of PYK2 was determined to be 254 nmol/min/mg using a poly (Glu:Tyr, 4:1) synthetic peptide substrate
Molecular Mass : In SDS-PAGE migrates as 39 kDa.
Purity : The purity was determined to be >90% by densitometry
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : PTK2B PTK2B protein tyrosine kinase 2 beta [ Homo sapiens ]
Official Symbol : PTK2B
Synonyms : PTK2B; PTK2B protein tyrosine kinase 2 beta; FAK2, protein tyrosine kinase 2 beta; protein-tyrosine kinase 2-beta; CADTK; CAKB; PTK; PYK2; RAFTK; FADK 2; CAK-beta; protein kinase B; focal adhesion kinase 2; cell adhesion kinase beta; proline-rich tyrosine kinase 2; calcium-dependent tyrosine kinase; related adhesion focal tyrosine kinase; calcium-regulated non-receptor proline-rich tyrosine kinase; PKB; FAK2; FADK2;
Gene ID : 2185
mRNA Refseq : NM_004103
Protein Refseq : NP_004094
MIM : 601212
UniProt ID : Q14289
Chromosome Location : 8p21.1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is PTK2B protein expression measured in clinical settings? 11/19/2022

PTK2B protein expression can be assessed using techniques like Western blotting and immunohistochemistry.

What are the challenges in developing PTK2B-targeted therapies? 10/27/2022

One of the challenges is achieving specificity in targeting PTK2B without affecting other related proteins or pathways.

Are there any drugs that target PTK2B protein? 06/22/2019

Several small molecule inhibitors targeting PTK2B are being developed as potential therapeutics for cancer and other diseases.

Can PTK2B protein be used as a diagnostic marker for any diseases? 06/09/2019

PTK2B protein expression has been explored as a potential diagnostic marker for certain cancers and neurodegenerative disorders.

Can PTK2B protein be targeted for therapeutic purposes? 12/21/2018

Yes, PTK2B is a potential therapeutic target for cancer, neurodegenerative diseases, and cardiovascular conditions.

Customer Reviews (3)

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Reviews
11/10/2021

    PTK2B protein is highly recommended for researchers, as it demonstrates excellent performance in WB experiments and has proven useful in protein electron microscopy structure analysis.

    04/28/2021

      PTK2B protein is highly recommended for researchers due to its excellent performance in various assays, particularly in Western blotting (WB) experiments, and its applicability in protein electron microscopy structure analysis.

      07/04/2018

        It enables accurate detection and quantification of PTK2B protein levels in samples, providing crucial insights into its expression, regulation, and potential functional changes under different experimental conditions.

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