Active Recombinant Human MAP3K5, GST-tagged
Cat.No. : | MAP3K5-578H |
Product Overview : | Recombinant Human MAP3K5 (Accession # NM_005923) amino acids 649 - 946, fused with an N-terminal GST tag, was produced in baculovirus in Sf 9 insect cells. |
- Specification
- Gene Information
- Related Products
Source : | Sf 9 insect cells |
Species : | Human |
Tag : | GST |
Form : | Supplied in 50 mM Tris HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol. |
Bio-activity : | The specific activity of ASK1 was determined to be 96 nmol/min/mg using a myelin basic protein (MBP) substrate |
Molecular Mass : | In SDS-PAGE migrates as 60 kDa. |
Purity : | The purity was determined to be >90% by densitometry |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | MAP3K5 mitogen-activated protein kinase kinase kinase 5 [ Homo sapiens ] |
Official Symbol : | MAP3K5 |
Synonyms : | MAP3K5; mitogen-activated protein kinase kinase kinase 5; MEKK5; apoptosis signal regulating kinase 1; ASK1; MAPKKK5; ASK-1; MEKK 5; MEK kinase 5; MAP/ERK kinase kinase 5; MAPK/ERK kinase kinase 5; apoptosis signal-regulating kinase 1; |
Gene ID : | 4217 |
mRNA Refseq : | NM_005923 |
Protein Refseq : | NP_005914 |
MIM : | 602448 |
UniProt ID : | Q99683 |
Chromosome Location : | 6q22.33 |
Products Types
◆ Recombinant Protein | ||
MAP3K5-1092H | Recombinant Human MAP3K5 Protein (M649-K946), His tagged | +Inquiry |
MAP3K5-1093H | Recombinant Human MAP3K5 Protein (M649-K946), GST/His tagged | +Inquiry |
Map3k5-3931M | Recombinant Mouse Map3k5 Protein, Myc/DDK-tagged | +Inquiry |
MAP3K5-1359H | Recombinant Human MAP3K5 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAP3K5-5333M | Recombinant Mouse MAP3K5 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MAP3K5-4504HCL | Recombinant Human MAP3K5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMAP3K5 has been implicated in various diseases, including neurodegenerative disorders, cardiovascular diseases, and inflammatory conditions.
Aberrant regulation of MAP3K5 has been associated with cancer development, as it can influence cell survival and death pathways.
MAP3K5 expression levels and activity may serve as biomarkers for specific diseases, providing valuable information for diagnosis and prognosis.
Research suggests that targeting MAP3K5 could have therapeutic implications in cancer treatment, potentially through the modulation of apoptosis in cancer cells.
Investigational studies and clinical trials are underway to explore the efficacy of MAP3K5 inhibitors in different disease contexts, including cancer.
Customer Reviews (3)
Write a reviewThe MAP3K5 protein has proven to be invaluable in protein electron microscopy structure analysis.
Its ability to provide accurate and reliable results in this particular application makes it a preferred choice for researchers studying antigen-antibody interactions and immune responses.
The MAP3K5 protein's sensitivity and specificity ensure precise measurements, contributing to the overall success of ELISA experiments.
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