Active Recombinant Feline FAS, Fc Chimera

• Cat.No.: FAS-635F
• Product Overview: Recombinant Feline FAS (Accession # NP_001009314) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Feline
• Tag: Fc Chimera
• Predicted N Terminal: Ala25
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit Fas Ligand-induced apoptosis of Jurkat human acute T cell leukemia cells.The ED50 for this effect is typically 1 - 4 µg/mL in the presence of 20 ng/mL of rhFas Ligand.
• Molecular Mass: Recombinant Feline FAS, Fc Chimera has a calculated MW of 43 kDa (monomer). In SDS-PAGE migrates as 59-61 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: FAS Fas cell surface death receptor [ Felis catus (domestic cat) ]
• Official Symbol: FAS
• Synonyms: FAS; Fas cell surface death receptor; TNFRSF6; tumor necrosis factor receptor superfamily member 6; Fas (TNF receptor superfamily, member 6); Fas antigen; tumor necrosis factor receptor superfamily, member 6
• Gene ID: 493881
• mRNA Refseq: NM_001009314
• Protein Refseq: NP_001009314
• Chromosome Location: D2