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Recombinant Human C10orf54, His-tagged

Cat.No. : C10orf54-837H
Product Overview : Recombinant Human C10orf54(Met1-Ala194) fussed with His tag at C-terminal was expressed in Human Cells.
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  • Gene Information
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Description : C10orf54, also known as GI24, belongs to the immunoglobulin superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. On ESCs, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state. On tumor cells, C10orf54 both promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. This increases the potential for cell motility. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
Source : Human Cells
Species : Human
Tag : His
Predicted N Terminal : Phe 33
Form : Lyophilized from sterile PBS, pH 7.4
Molecular Mass : The recombinant human Gi24 consists of 173 amino acids and predicts a molecular mass of 19.6 KDa. It migrates as an approximately 38-42 KDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Usage : FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE
Stability : Samples are stable for up to twelve months from date of receipt at -70 centigrade
Storage : Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : C10orf54 chromosome 10 open reading frame 54 [ Homo sapiens ]
Official Symbol : C10orf54
Synonyms : B7H5; GI24; B7-H5; SISP1; PP2135; platelet receptor Gi24; sisp-1; stress induced secreted protein 1; stress-induced secreted protein-1
Gene ID : 64115
mRNA Refseq : NM_022153
Protein Refseq : NP_071436
MIM : 615608
UniProt ID : Q9H7M9
Chromosome Location : 10q22.1

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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