Active Recombinant Mouse Agrp

• Cat.No.: Agrp-588M
• Product Overview: Recombinant Mouse Agrp (Accession # NP_031453) Ser82-Thr131, fused with , was produced in E. coli.

Specification

• Source: E. coli
• Species: Mouse
• Predicted N Terminal: Ser82
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to antagonize alpha -MSH-induced cAMP accumulation in HEK293 human embryonic kidney cells transfected with human Melanocortin-4 Receptor. Ollmann, M.M. et al. (1997) Science 278:135.The ED50 for this effect is typically 0.025-0.15 µg/mL in the presence of 10 ng/mL of alpha -MSH.
• Molecular Mass: Recombinant Mouse Agrp has a calculated MW of 5.7 kDa.
• Protein length: Ser82-Thr131
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Agrp agouti related protein [ Mus musculus ]
• Official Symbol: Agrp
• Synonyms: AGRP; agouti related protein; agouti-related protein; orexigenic neuropeptide; Art; Agrt
• Gene ID: 11604
• mRNA Refseq: NM_007427
• Protein Refseq: NP_031453