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Active Recombinant Mouse Sema5a Protein, Fc Chimera

Cat.No. : Sema5a-617M
Product Overview : Recombinant Mouse Sema5a (Accession # NP_033180), fused with , was produced in Chinese Hamster Ovary cell line, CHO-derived.
  • Specification
  • Gene Information
  • Related Products
Source : CHO Cells
Species : Mouse
Tag : Fc
Predicted N Terminal : Glu23
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of human pancreatic cancer cells.The ED50 for this effect is typically 0.9 - 3.6 µg/mL.
Molecular Mass : Recombinant Mouse Sema5a, Fc Chimera has a calculated MW of 110.8 kDa (monomer). In SDS-PAGE migrates as 120-140 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : Sema5a sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A [ Mus musculus ]
Official Symbol : Sema5a
Synonyms : SEMA5A; sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A; semaphorin-5A; sema F; M-Sema D; semaphorin F; semaphorin-F; semF; Semaf; AI464145; 5930434A13; 9130201M22Rik;
Gene ID : 20356
mRNA Refseq : NM_009154
Protein Refseq : NP_033180
MIM :

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the primary function of Semaphorin-5A (SEMA5A) in cellular processes and neural development? 06/10/2021

Semaphorin-5A (SEMA5A) functions in cellular processes, primarily playing a role in neural development and axon guidance.

In which cellular compartments is SEMA5A predominantly localized, especially within the nervous system? 11/27/2019

SEMA5A is predominantly localized in growth cones and axonal pathways within the nervous system.

Are there therapeutic implications or potential targets related to SEMA5A in neurological disorders involving neural development? 08/10/2018

There are potential therapeutic implications related to SEMA5A in neurological disorders involving neural development, making it a target for drug development.

How does SEMA5A participate in axon guidance and neuronal migration during neural development? 05/25/2018

SEMA5A participates in axon guidance and neuronal migration during neural development by interacting with Plexin-A and Neuropilin-1 receptors.

Are there specific receptors or co-receptors that SEMA5A interacts with, influencing its role in neural circuit formation? 02/27/2018

Specific receptors or co-receptors that SEMA5A interacts with include Plexin-A and Neuropilin-1, influencing its role in neural circuit formation.

How does SEMA5A contribute to the regulation of synaptic connectivity and plasticity in the nervous system? 09/05/2016

SEMA5A contributes to the regulation of synaptic connectivity and plasticity in the nervous system, impacting neural circuit formation.

What diseases or conditions are associated with dysregulation or abnormal expression of SEMA5A? 05/11/2016

Dysregulation or abnormal expression of SEMA5A is associated with conditions such as autism spectrum disorders and developmental disorders.

Customer Reviews (3)

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Reviews
11/15/2022

    The product's consistent outcomes fortified the reproducibility of our scientific inquiries.

    03/26/2021

      Despite its cost, the product's contributions to our research goals made it an invaluable asset.

      03/09/2019

        We appreciated the product's efficiency in achieving target protein upregulation with minimal time investment.

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