Active Recombinant Mouse Sema5a Protein, Fc Chimera
Cat.No. : | Sema5a-617M |
Product Overview : | Recombinant Mouse Sema5a (Accession # NP_033180), fused with , was produced in Chinese Hamster Ovary cell line, CHO-derived. |
- Specification
- Gene Information
- Related Products
Source : | CHO Cells |
Species : | Mouse |
Tag : | Fc |
Predicted N Terminal : | Glu23 |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS. |
Bio-activity : | Measured by the ability of the immobilized protein to support the adhesion of human pancreatic cancer cells.The ED50 for this effect is typically 0.9 - 3.6 µg/mL. |
Molecular Mass : | Recombinant Mouse Sema5a, Fc Chimera has a calculated MW of 110.8 kDa (monomer). In SDS-PAGE migrates as 120-140 kDa, reducing conditions. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Reconstitution : | Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Gene Name : | Sema5a sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A [ Mus musculus ] |
Official Symbol : | Sema5a |
Synonyms : | SEMA5A; sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A; semaphorin-5A; sema F; M-Sema D; semaphorin F; semaphorin-F; semF; Semaf; AI464145; 5930434A13; 9130201M22Rik; |
Gene ID : | 20356 |
mRNA Refseq : | NM_009154 |
Protein Refseq : | NP_033180 |
MIM : |
Products Types
◆ Recombinant Protein | ||
Sema5a-8692M | Recombinant Mouse Sema5a protein(Met1-Thr765), His-tagged | +Inquiry |
Sema5a-5762M | Recombinant Mouse Sema5a Protein, Myc/DDK-tagged | +Inquiry |
SEMA5A-2680H | Recombinant Human SEMA5A Protein, His-tagged | +Inquiry |
SEMA5A-4973R | Recombinant Rat SEMA5A Protein, His (Fc)-Avi-tagged | +Inquiry |
SEMA5A-1969H | Recombinant Human SEMA5A Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SEMA5A-1860HCL | Recombinant Human SEMA5A cell lysate | +Inquiry |
SEMA5A-1310MCL | Recombinant Mouse SEMA5A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionSemaphorin-5A (SEMA5A) functions in cellular processes, primarily playing a role in neural development and axon guidance.
SEMA5A is predominantly localized in growth cones and axonal pathways within the nervous system.
There are potential therapeutic implications related to SEMA5A in neurological disorders involving neural development, making it a target for drug development.
SEMA5A participates in axon guidance and neuronal migration during neural development by interacting with Plexin-A and Neuropilin-1 receptors.
Specific receptors or co-receptors that SEMA5A interacts with include Plexin-A and Neuropilin-1, influencing its role in neural circuit formation.
SEMA5A contributes to the regulation of synaptic connectivity and plasticity in the nervous system, impacting neural circuit formation.
Dysregulation or abnormal expression of SEMA5A is associated with conditions such as autism spectrum disorders and developmental disorders.
Customer Reviews (3)
Write a reviewThe product's consistent outcomes fortified the reproducibility of our scientific inquiries.
Despite its cost, the product's contributions to our research goals made it an invaluable asset.
We appreciated the product's efficiency in achieving target protein upregulation with minimal time investment.
Ask a Question for All Sema5a Products
Required fields are marked with *
My Review for All Sema5a Products
Required fields are marked with *
Inquiry Basket