Active Recombinant Mouse Bmpr1a Protein, Fc Chimera

• Cat.No.: Bmpr1a-623M
• Product Overview: Recombinant Mouse Bmpr1a (Accession # NP_033888), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Mouse
• Tag: Fc
• Predicted N Terminal: No results obtained: Gln24 predicted, N-sequencing might be blocked
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit rhBMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al. (1999) Exp. Cell Res. 250:351.The ED50 for this effect is typically 0.03 - 0.12 µg/mL in the presence of 30 ng/mL of recombinant human BMP-4.
• Molecular Mass: Recombinant Mouse Bmpr1a, Fc Chimera has a calculated MW of 41.3 kDa (monomer). In SDS-PAGE migrates as 57-60 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 10 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: Bmpr1a bone morphogenetic protein receptor, type 1A [ Mus musculus ]
• Official Symbol: Bmpr1a
• Synonyms: BMPR1A; bone morphogenetic protein receptor, type 1A; bone morphogenetic protein receptor type-1A; SKR5; ALK-3; BMPR-1A; BMP type-1A receptor; BMP-2/BMP-4 receptor; activin receptor-like kinase 3; serine/threonine-protein kinase receptor R5; ALK3; Bmpr; BMPR-IA; AU045487; 1110037I22Rik
• Gene ID: 12166
• mRNA Refseq: NM_009758
• Protein Refseq: NP_033888