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Active Recombinant Mouse Nt5e Protein, His-tagged

Cat.No. : Nt5e-667M
Product Overview : Recombinant Mouse Nt5e (Accession # NP_035981) Trp29-Lys549, fused with a C-terminal 6-His tag, was produced in Chinese Hamster Ovary cell line, CHO-derived.
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  • Gene Information
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Source : CHO Cells
Species : Mouse
Tag : His
Predicted N Terminal : Trp29
Form : Supplied as a 0.2 µm filtered solution in Tris, NaCl, CaCl2 and Glycerol.
Bio-activity : Measured by its ability to hydrolyze the 5"-phosphate group from the substrate adenosine-5"-monophosphate (AMP). The orthophosphate product is measured by a Malachite Green Phosphate Detection Kit.The specific activity is >10,000 pmol/min/µg, as measured under the described conditions.
Molecular Mass : Recombinant Mouse Nt5e, His-tagged has a calculated MW of 59 kDa. In SDS-PAGE migrates as 60 kDa, reducing conditions.
Protein length : Trp29-Lys549
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : Nt5e 5 nucleotidase, ecto [ Mus musculus ]
Official Symbol : Nt5e
Synonyms : NT5E; 5 nucleotidase, ecto; 5-nucleotidase; 5-NT; ecto-5-nucleotidase; NT; Nt5; eNT; CD73; AI447961; 2210401F01Rik;
Gene ID : 23959
mRNA Refseq : NM_011851
Protein Refseq : NP_035981
MIM :

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can NT5E be used as a biomarker for certain diseases? 03/22/2023

Yes, elevated levels of NT5E have been observed in various diseases, making it a potential biomarker for conditions such as cancer and autoimmune disorders.

How does NT5E contribute to inflammation? 11/02/2022

NT5E-generated adenosine has anti-inflammatory effects, and modulating NT5E activity is being explored as a potential therapeutic strategy for inflammatory conditions.

Is NT5E associated with autoimmune diseases? 05/26/2021

Yes, NT5E is implicated in autoimmune diseases, and targeting its activity is being investigated for potential therapeutic interventions.

Are there any FDA-approved drugs targeting NT5E for cancer treatment? 03/10/2020

As of my last knowledge update in January 2022, there were no FDA-approved drugs specifically targeting NT5E, but research in this area is ongoing.

How is NT5E linked to neurological disorders? 12/11/2017

NT5E-generated adenosine is neuroprotective, and research is exploring its potential in the treatment of neurodegenerative disorders.

Customer Reviews (3)

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Reviews
11/20/2022

    the manufacturer's support plays a crucial role in the successful implementation of trials involving the NT5E protein.

    09/01/2017

      The manufacturer maintains stringent quality control measures to ensure the purity and stability of the protein, minimizing experimental variability and maximizing the accuracy of the data obtained.

      01/25/2017

        Their responsiveness to inquiries and willingness to address concerns contribute to a smooth and productive research experience.

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