Active Recombinant Human TWSG1

• Cat.No.: TWSG1-729H
• Product Overview: Recombinant Human TWSG1 (Accession # NP_065699) Met1-Phe223, fused with , was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Source: CHO Cells
• Species: Human
• Predicted N Terminal: Cys26
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit BMP-6-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells.The ED50 for this effect is typically 4 - 16 µg/mL in the presence of 100 ng/mL of Recombinant Human BMP-6.
• Molecular Mass: Recombinant Human TWSG1 has a calculated MW of 22.1 kDa. In SDS-PAGE migrates as 35-43 kDa, reducing conditions.
• Protein length: Met1-Phe223
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: TWSG1 twisted gastrulation homolog 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: TWSG1
• Synonyms: TWSG1; twisted gastrulation homolog 1 (Drosophila); twisted gastrulation protein homolog 1; TSG
• Gene ID: 57045
• mRNA Refseq: NM_020648
• Protein Refseq: NP_065699
• MIM: 605049
• UniProt ID: Q9GZX9
• Chromosome Location: 18p11.3