Active Recombinant Human IFNL2

• Cat.No.: IFNL2-845H
• Product Overview: Recombinant Human IFNL2 (Accession # NP_742150), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Predicted N Terminal: Val26
• Form: Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
• Bio-activity: Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Sheppard, P. et al. (2003) Nat. Immunol. 4:63.The ED50 for this effect is typically 10-50 ng/mL.
• Molecular Mass: Recombinant Human IFNL2 has a calculated MW of 20.8 kDa. In SDS-PAGE migrates as 24 kDa, reducing conditions.
• Purity: >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: IFNL2 interferon, lambda 2 [ Homo sapiens (human) ]
• Official Symbol: IFNL2
• Synonyms: IL28A; IL-28A; interferon lambda-2; interferon lambda-2; IFN-lambda-2; cytokine Zcyto20; interferon lambda 2; interferon-lambda 2; interleukin 28A (interferon, lambda 2); interleukin-28A
• Gene ID: 282616
• mRNA Refseq: NM_172138.1
• Protein Refseq: NP_742150.1
• MIM: 607401
• UniProt ID: Q8IZJ0
• Chromosome Location: 19q13.13