Active Recombinant Mouse Tnfrsf11a Protein, Fc Chimera

• Cat.No.: Tnfrsf11a-955M
• Product Overview: Recombinant Mouse Tnfrsf11a (Accession # O35305.1), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Mouse
• Tag: Fc
• Predicted N Terminal: Met
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit TRANCE-induced osteoclast differentiation of mouse splenocytes.The ED50 for this effect is typically 0.05 - 0.15 µg/mL in the presence of 10 ng/mL of rmTRANCE.
• Molecular Mass: Recombinant Mouse Tnfrsf11a, Fc Chimera has a calculated MW of 48 kDa (monomer). In SDS-PAGE migrates as 60 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a [ Mus musculus ]
• Official Symbol: Tnfrsf11a
• Synonyms: TNFRSF11A; tumor necrosis factor receptor superfamily, member 11a; tumor necrosis factor receptor superfamily member 11A; receptor activator of NF-KB; receptor activator of NF-kappaB; osteoclast differentiation factor receptor; OFE; ODFR; Rank; Ly109; mRANK; TRANCE-R
• Gene ID: 21934
• mRNA Refseq: NM_009399
• Protein Refseq: NP_033425